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Narcolepsy and Hypoglycaemia

Published online by Cambridge University Press:  08 February 2018

Colin M. Smith  and
R. A. Schneider
Colin M. Smith
Affiliation:
Psychiatric Research, Department of Public Health University Hospital, Saskatoon, Saskatchewan
R. A. Schneider
Affiliation:
University Hospital, Saskatoon, Saskatchewan
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Extract

For some years now it has been recognized that the symptoms induced by hypoglycaemia may resemble narcolepsy. Cases of islet-celled pancreatic adenomas simulating narcolepsy have been described by Harris (7), Delay (4) and Wyke (18). The resemblance may be a superficial one, however, and Wyke observed in his case during a “sleepy attack” that “the EEG pattern bore no resemblance to that of natural or artificial sleep”. In a more recent paper Ziegler and Presthus (19) described thirteen patients who showed normal EEGs at blood glucose levels (induced by fasting and intravenous insulin) of from under 15 mg. per cent. to 54 mg. per cent. In eight of these patients there were no clinical symptoms; in the remaining five patients the symptoms were described as follows: “feel like a ton of lead”, “warm and sleepy”, “tired”, “drowsy and sweaty” and “dizzy and tired”. It seems, in fact, that the clinical description of drowsiness in hypoglycaemia may correspond either to no EEG changes or to various degrees of slowing rather than to the typical recurrent light sleep patterns characteristic of narcolepsy. It will be recalled that hypnosis too is ushered in by a sense of drowsiness but that the EEG changes are not those of sleep (1, 2, 5). Many hysterical trance states—often loosely, and unfortunately, described as narcolepsy—come into this category. In short, it is apparent that all that sleeps is not narcolepsy (6, 12, 13, 14).

Type
Original Articles
Information
Journal of Mental Science , Volume 105 , Issue 438 , January 1959 , pp. 163 - 170
Copyright
Copyright © Royal College of Psychiatrists, 1959 

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References

1. Barker, W., and Burgwin, S., “Brain Wave Patterns accompanying Changes in Sleep and Wakefulness during Hypnosis”, Psychosom. Med., 1948, 10, 317–326.CrossRefGoogle Scholar
2. Idem , “Brain Wave Patterns during Hypnosis, Hypnotic Sleep and Normal Sleep”, A.M.A. Arch. Neurol. Psychiat., 1949, 62, 412–420.Google Scholar
3. Daly, D. D., and Yoss, R. E., “Electroencephalogram in Narcolepsy”, EEG Clin. Neurophys., 1957, 9, 109–120.Google Scholar
4. Delay, J., “Narcolepsie et Hypoglycemie”, Ann. Méd.-Psychol., 1942, 100, 375–379.Google Scholar
5. Dynes, J. B., “Objective Method for Distinguishing Sleep from the Hypnotic Trance”, A.M.A. Arch. Neurol. Psychiat., 1947, 57, 84–93.CrossRefGoogle Scholar
6. Goldstein, N. P., and Giffin, M. E., “Functional Hypersomnia (‘Pseudo-narcolepsy’)”, Paper read at A.P.A. Annual Meeting, 1958.Google Scholar
7. Harris, S., “Epilepsy and Narcolepsy Associated with Hyperinsulinism”, J.A.M.A., 1933, 100, 321–328.Google Scholar
8. Hoffer, A., “Induction of Sleep by Autonomic Drugs”, J. Nerv. Ment. Dis., 1954, 119, 421–427.Google Scholar
9. Idem. Personal communication, 1957.Google Scholar
10. Rothballer, A. B., “Studies of the Adrenaline-Sensitive Component of the Reticular Activating System”, EEG Clin. Neurophysiol., 1956, 8, 603–621.Google Scholar
11. Idem , “The Effect of Phenylephrine, Methamphetamine, Cocaine and Serotonin upon the Adrenaline-Sensitive Component of the Reticular Activating System”, ibid., 1957, 9, 409–417.Google Scholar
12. Smith, C. M., “Comments and Observations on Psychogenic Hypersomnia”, A.M.A. Arch. Neurol. Psychiat. (In press.)Google Scholar
13. Idem , “Psychosomatic Aspects of Narcolepsy”, J. Ment. Sci. 1958, 104, 593–607.Google Scholar
14. Idem , “Psychosomatic Aspects of Narcolepsy”. 1958. Unpublished M.D. Thesis submitted to University of Glasgow.Google Scholar
15. Szatmari, A., and Schneider, R. A., “Induction of Sleep by Autonomic Drugs”, J. Nerv. Ment. Dis., 1955, 121, 311–320.Google Scholar
16. Weitzner, H. A., “Insulin Hypoglycaemia in the Treatment of Narcolepsy with Temporary Improvement”, Permanente Found. Bull., 1952, 10, 153–158.Google Scholar
17. Idem , “Sleep Paralysis successfully treated with Insulin Hypoglycaemia”, A.M.A. Arch. Neurol. Psychiat., 1952, 88, 835–841.Google Scholar
18. Wyke, B. D., “Brain Function and Blood Sugar: Observations based on a Case of Islet Cell Adenoma of the Pancreas”, EEG Clin. Neurophysiol., 1952, 4, 339–350.Google Scholar
19. Ziegler, D. K., and Presthus, J., “Normal EEG at Deep Levels of Hypoglycaemia”, ibid., 1957, 9, 523–526.Google Scholar
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