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Hydroxyzine (Atarax) in the Relief of Tension Associated with Anxiety Neurosis and Mild Depressive States

Published online by Cambridge University Press:  08 February 2018

R. Middlefell  and
K. C. S. Edwards
R. Middlefell
Affiliation:
Deva Hospital, Chester
K. C. S. Edwards
Affiliation:
Deva Hospital, Chester
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Extract

Turle (1) in a double-blind trial using hydroxyzine found that of 18 patients admitted to a neurosis unit (7 anxiety neurosis, 1 obsessive-compulsive state, 6 depressive states and 1 involutional melancholia) only 3 patients showed signs of improvement on a dosage of 30 mg. by mouth, t.d.s. Only 1 out of 8 selected on account of tension symptoms was relieved. The other 2 improved cases were depressive cases with secondary anxiety features. He concluded that the drug was of no manifest benefit in neurotics. The serene tension-free effect reputedly produced by the drug and described by American workers was not observed.

Type
Original Articles
Information
Journal of Mental Science , Volume 105 , Issue 440 , July 1959 , pp. 792 - 794
Copyright
Copyright © Royal College of Psychiatrists, 1959 

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References

Turle, G. C., J. Ment. Sci., 1958, 104, 826.Google Scholar
Seneca, H., Antibiot. Med. & Clin. Therapy, Brit ed., 1957, 2, 1.Google Scholar
Raymond, et al., Brit. Med. J., 13 July 1957, page 64.Google Scholar
Edwards, A. L., Statistical Methods for the Behavioural Sciences, 1954 ed.Google Scholar
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