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The Effects of Promazine (“Sparine”) in Chronic Schizophrenia

Published online by Cambridge University Press:  08 February 2018

R. Wallace Simpson  and
J. G. Jesson
R. Wallace Simpson
Affiliation:
Knowle Hospital, Fareham
J. G. Jesson
Affiliation:
Knowle Hospital, Fareham
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Extract

Promazine hydrochloride (“Sparine”) is a phenothiazine derivative which has recently been introduced to this country with claims to be a “tranquillizing” drug. It is closely related chemically to chlorpromazine but does not contain the chlorine atom which has been thought to cause the undesirable side effects of the promazine group. The structural formula of Sparine compares with that of chlorpromazine as follows:

Type
Original Articles
Information
Journal of Mental Science , Volume 104 , Issue 437 , October 1958 , pp. 1199 - 1202
Copyright
Copyright © Royal College of Psychiatrists, 1958 

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References

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