Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-22T13:10:44.359Z Has data issue: false hasContentIssue false
  • English
  • Français

Effects of Electrical Stimulation of the Brain on the Concentration of Adrenaline-Like Substances in Human Plasma

Published online by Cambridge University Press:  08 February 2018

J. D. Montagu
J. D. Montagu*
Affiliation:
Runwell Hospital, Wickford, Essex
Get access Rights & Permissions [Opens in a new window]

Extract

Cerebral electrostimulation of subconvulsive intensity causes an increase in the concentration of adrenaline-like substances in the blood (Weil-Malherbe and Bone, 1952b). This increase becomes more pronounced as the pulse repetition rate is raised from 200 pulses per second (p.p.s.) to 500 p.p.s., in contrast to the motor, sensory, and respiratory effects which diminish under these conditions (Montagu, 1955). The increasing response to the higher repetition rates showed no sign of reaching a peak in these experiments, except in one case, and since it was not possible with the existing apparatus to exceed 500 p.p.s., the optimal conditions for eliciting the response remained undetermined. With the aid of a more versatile stimulator the adrenaline-frequency relationship has subsequently been studied more extensively, and the results are presented in this article.∗

Type
Original Articles
Information
Journal of Mental Science , Volume 104 , Issue 434 , January 1958 , pp. 182 - 187
Copyright
Copyright © Royal College of Psychiatrists, 1958 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Anonymous, “Annotation: Adrenaline and mental activity”, Brit. med. J., 1956, i, 448.Google Scholar
Mihailovic, L., and Delgado, J. M. R., “Electrical stimulation of monkey brain with various frequencies and pulse durations”, J. Neurophysiol., 1956, 19, 21–36.Google Scholar
Montagu, J. D., “Differential cerebral electrostimulation”, J. Ment. Sci., 1955, 101, 110–122.Google Scholar
Renton, G. H., and Weil-Malherbe, H., “Adrenaline and noradrenaline in human plasma during natural sleep”, J. Physiol., 1956, 131, 170–175.Google Scholar
Weil-Malherbe, H., “The effect of convulsive therapy on plasma adrenaline and noradrenaline”, J. Ment. Sci., 1955, 101, 156–162.Google Scholar
Idem , “Correspondence: Adrenaline and mental activity”, Brit. med. J., 1956, i, 748.Google Scholar
Idem , 1957. In preparation.Google Scholar
Idem and Bone, A. D., “The chemical estimation of adrenaline-like substances in blood”, Biochem. J., 1952a, 51, 311–318.Google Scholar
Iidem , “The concentration of adrenaline-like substances in blood during insulin hypoglycaemia”, J. Ment. Sci., 1952b, 98, 565–578.Google Scholar
Iidem , “The adrenergic amines of human blood”, Lancet, 1953. i, 974–977.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.