Published online by Cambridge University Press: 19 February 2018
It is only within the last two or three years that alienists have learnt to recognize the importance of the existence in cases of progressive paralysis of the insane of certain extremely interesting neuro-muscular anatomical alterations. Too long was the teaching of Lockhart Clarke,1 Tigges,2 Westphal,3 Magnan,4 Voisin,5 Mendel,6 etc., that the cerebrospinal changes represented the sole anatomical substratum of the clinical features in this disease, regarded as infallible, and it is pleasing to think that our erroneous conceptions have been removed by the energetic researches and discoveries of another generation, including among their number Déjerine,7 Lubimoff,8 Mierzejewski,9 Bianchi,10 Fürst-
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