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A Contribution to the Morbid Anatomy and Pathology of the Neuro-Muscular Changes in General Paralysis of the Insane

Published online by Cambridge University Press:  19 February 2018

Alfred W. Campbell*
Affiliation:
County Asylum, Rainhill, Lancashire

Extract

It is only within the last two or three years that alienists have learnt to recognize the importance of the existence in cases of progressive paralysis of the insane of certain extremely interesting neuro-muscular anatomical alterations. Too long was the teaching of Lockhart Clarke,1 Tigges,2 Westphal,3 Magnan,4 Voisin,5 Mendel,6 etc., that the cerebrospinal changes represented the sole anatomical substratum of the clinical features in this disease, regarded as infallible, and it is pleasing to think that our erroneous conceptions have been removed by the energetic researches and discoveries of another generation, including among their number Déjerine,7 Lubimoff,8 Mierzejewski,9 Bianchi,10 Fürst-

Type
Part I.—Original Articles
Copyright
Copyright © Royal College of Psychiatrists, 1894 

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References

1 “On the Morbid Anatomy of the Nervous Centres in General Paralysis of the Insane.” “Lancet,” Sept., 1866.Google Scholar
2 “Pathologische, anatomische und physiologische Untersuchungen über Dementia progressiva paralytica.” “Allg. Zeitschr. f. Psychiatrie,” Bd. xx.Google Scholar
3 (a.) “Über Erkrankungen des Rückenmarkes bei der allgemeinen progressiven Paralyse der Irren.” “Virchow's Archiv.,” 1867.Google Scholar
(b.) “Ueber den gegenwärtigen Standpunkt der Kenntnisse von der Allgemeinen progressiven Paralyse der Irren.” “Arch, für Psych, und Nervenkrank.,” Berlin, 1868.Google Scholar
4 “De la lésion anatomique de la paralysie générale.” Thése de Paris, 1866.Google Scholar
5 “Traité de la Paralysie générale des Aliénés.” Paris, 1879.Google Scholar
6 “Die progressive Paralyse der Irren.” 1880.Google Scholar
7 “Archiv. de Physiologie,” p. 317. 1876.Google Scholar
8 “Virch. Archiv.,” Bd. 57, p. 371.Google Scholar
9 “Archiv. de Physiologie,” 1875, p. 195.Google Scholar
10 “La base anatomica della paralisi progressiva.” “Ricerche istologische.” 1887.Google Scholar

Neuro-Muscular Changes in General Paralysis,

11 “Zur Path. und Path. Anatom. der prog. Paral. imbesondere über die Veränderungen des Bückenmarkes und der peripheren Nerven.” “Arch. f. Psych.,” Berlin, 1892, 24.Google Scholar
12 “West Riding Asylum Reports,” Vol. 5., 1875.Google Scholar
13 “Annali di Neurologia,” 1891, pp. 115200.Google Scholar
14 “Brain,” 1892, p. 241.Google Scholar
* The entire material, both clinical and pathological, for my observations has been afforded by the County Asylum, Rainhill.Google Scholar
15 “Von Kahlden. Technik der histologischen Untersuchung pathologisch-anatomischer Präparate.” Jena, 1892, p. 97.Google Scholar
16 “Von Kahlden.,” p. 90.Google Scholar
* A brief account of this case was given by Dr. Wiglesworth in this Journal in his paper on “General Paralysis about the Period of Puberty,” July, 1893.Google Scholar
17 “Contribution à Pétude de la névrite alcoolique.” “Arch, de phys. norm. et path.,” 1887.Google Scholar
18 “Alcoholic Paralysis of the Phrenic, Pneumogastric, and other Nerves.” “Transactions of the Path. Soc. London,” 1888.Google Scholar
19 “Ein Beitrag zur path. Anatomie der sog. Polyneuritis alcoholica,” “Zeitschrift für Heilkunde,” Prag., 1892.Google Scholar
20 (a) “Journal of Mental Science,” Apr., 1872, p. 31.Google Scholar
20 (b) “On General Paralysis of the Insane,” 2nd Ed., p. 186.Google Scholar
21 “Ein Fall von Vaguserkrankung bei progressiver Paralyse.” “Allg. Zeitschrift für Psychiatrie, Berlin,” 1888, 44, p. 495.Google Scholar
22 “La pulmonite dei paralytici e la degenerazione dei nervi vaghi.” La Psichiatria, 1889.Google Scholar
23 “Les Nerfs vasomoteurs,” 5., ii.Google Scholar
24 Loc. cit. (b), p. 296. This writer found tubercle in an average of 25 per cent.Google Scholar
25 “The Pulmonary Pathology of General Paralysis.” “Brain,” 1883-84, 6., pp. 317341.Google Scholar
26 “Tabes mit Zwerchfellslähmung.” “Berliner klinische Wochenschrift,” No. xvi., 1893.Google Scholar
* Sc called by Vanlair, Déjerine, Gombault, etc.; described as “degenerative atrophy,” or simple degeneration of the nerve fibres, by others.Google Scholar
27 “Beitrag zur Kenntniss der multiplen degeneratiren Neuritis.” “Zeitsch. für Klin. Med.,” 1891.Google Scholar
28 “Neuritis fascians. Ein Beitrag zur Lehre von der Alcoholneuritis.” “Virchow Archiv.,” 112 B., 1888.Google Scholar
29 Note on optic nerve atrophy preceding the mental symptoms of General Paralysis of the Insane. “Journal Ment. Sci.,” 1889, pp. 389391.Google Scholar
30 “Text-Book of Mental Diseases,” London, 1889, p. 283.Google Scholar
31 “Ein Fall von Alcoholneuritis mit hervorragender Betheiligung des Muskel apparates.” “Charitè Annalen,” 1889.Google Scholar
32 “Lésions des poumons du cœur, du foie et des reins dans la paralysie générate.” “Archives de méd. expérimentale,” July 1, 1892.Google Scholar
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