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Clinico-Anatomical Studies of Frontal Lobe Function Based on Leucotomy Material

Published online by Cambridge University Press:  08 February 2018

A. Meyer  and
T. McLardy
A. Meyer
Affiliation:
From the Department of Neuropathology, Research Laboratory, Maudsley Hospital, London
T. McLardy
Affiliation:
From the Department of Neuropathology, Research Laboratory, Maudsley Hospital, London
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Extract

The present paper is based upon the investigation of 95 brains of patients dying some time after leucotomy, and mainly, though not exclusively, upon the 45 cases in which the survival period was more than 5 months (up to 5 years). In a third of the total material and in about half of the 45 cases with survival longer than 5 months a full microscopical investigation has been carried out or is nearing completion. Eventually all the informative cases will have been so examined, but investigation by serial sections of considerable parts of the brain is a time-consuming undertaking. An unfortunately irremediable defect in our material is the unevenness and incompleteness of the clinical, physiological and psychological investigations of the patients. Obviously only limited correlation studies can be carried out on such material. Again, the number of fully recovered cases in our material is small, in fact only some four (Nos. 66, 71, 10 and 18) of the total could be classed as such. The reason for this is that fully recovered patients are likely to die from intercurrent disease outside mental hospitals, when it is difficult to procure a post-mortem.

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 95 , Issue 399 , April 1949 , pp. 403 - 417
Copyright
Copyright © Royal College of Psychiatrists, 1949 

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