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Clinical Trials with Melleril (TP21) in the Treatment of Schizophrenia

A Two-Year Study

Published online by Cambridge University Press:  08 February 2018

R. A. Sandison ,
Eileen Whitelaw  and
J. D. C. Currie
R. A. Sandison
Affiliation:
Powick Hospital, near Worcester
Eileen Whitelaw
Affiliation:
Powick Hospital, near Worcester
J. D. C. Currie
Affiliation:
Powick Hospital, near Worcester
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Extract

The authors undertook to investigate the effects of two new phenothiazine derivatives on schizophrenic patients. Over a period of two years a series of clinical trials have been carried out on approximately 260 patients, some controlled, some uncontrolled. These drugs, known as Melleril (TP21) and KS75 are chemically related. Although Melleril was ultimately selected as the drug of choice we have, for statistical reasons, included some of the findings with KS75.

Type
Original Articles
Information
Journal of Mental Science , Volume 106 , Issue 443 , April 1960 , pp. 732 - 741
Copyright
Copyright © Royal College of Psychiatrists, 1960 

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References

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