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The Blood Barbiturate During Prolonged Narcosis

Published online by Cambridge University Press:  08 February 2018

R. F. Chatfield  and
D. N. Parfitt
R. F. Chatfield
Affiliation:
The Central Hospital, Warwick
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Extract

G. A. Levvy in 1940 (Biochem. J., 34, 73) published from the Department of Pharmacology, University of Edinburgh, a new method for the estimation of barbiturates in blood, claiming that his technique gave results accurate to a 20 per cent. error or less for quantities of 1.0 mgm. or more in 20 c.c. of blood. After studying this method at first hand we have carried out a number of estimations in cases undergoing prolonged narcosis with somnifaine, and studied the blood levels of barbiturates in patients under medication with soluble barbitone and phenobarbitone, a total of 200 estimations having been made.

Type
Part II.—Original Articles
Information
Journal of Mental Science , Volume 88 , Issue 373 , October 1942 , pp. 566 - 569
Copyright
Copyright © Royal College of Psychiatrists, 1942 

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