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Atrophy and Sclerosis of the Cerebellum

Published online by Cambridge University Press:  19 February 2018

C. Hubert Bond
C. Hubert Bond*
Affiliation:
London County Asylum, Banstead
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Extract

Notwithstanding all the elaborate researches that already have been conducted upon the cerebellum, much controversy yet exists as to its physiology, and a complete account of its functional relations, with the rest of the central nervous system, cannot yet be given. Rapid strides have been lately made, and many doubtful points elucidated by direct experiment upon lower animals, but the deductions drawn from them cannot be regarded as absolutely applicable to man until they have been confirmed by pathological observations on the human brain. With this in view, the case about to be related has been thought worthy of publication.

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 41 , Issue 174 , July 1895 , pp. 409 - 420
Copyright
Copyright © Royal College of Psychiatrists, 1895 

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References

† “Brain,” Spring, 1894.Google Scholar

∗ To Dr. Claye Shaw I am indebted for permission to publish this case, and to Dr. Fenoulhet for kindly supplying me with the notes made as to the patient's condition while at Hoxton House.Google Scholar

∗ In a case reported by Dr. Fletcher Beach in “Brain,” 1884, where there was atrophy of the left cerebral hemisphere and of the right half of the cerebellum, the cranium was asymmetrical, the corresponding fossæ being reduced in size.Google Scholar

∗ Vide “Tuke's Dictionary of Psychological Medicine.” Google Scholar

∗ “Journal of Mental Science,” Vol. 28.Google Scholar

† “Journal of Mental Science,”, Vol. 25.Google Scholar

∗ “St. Bartholomew's Hospital Reports,” Vol. 24.Google Scholar

∗ Permission has been kindly granted me to reproduce a drawing of a section through the cerebellum of one of these kittens.Google Scholar

† “Arch. f. Psychiatrie,” 16.Google Scholar

∗ ∗“British Medical Journal,” September, 1894.Google Scholar

† ∗Since reading this paper I note that, in the first part of “Brain” for this year, another case of a cat showing defective development of the central nervous system has been very fully reported on by Dr. Risien Russell. In this instance, among other defects, the right lateral lobe of the cerebellum was affected. The right half of the middle lobe did not appear to share in the atrophy. What existed of the right lateral lobe seemed fairly healthy. The proportion of the layers of the cortex to each other and of the grey to the white matter remained unaltered. The cells of Purkinjé were normal in appearance and arrangement, as were also the cells of the granular and molecular layers. In fact, it seemed rather as if part of this lobe had been simply removed. The corpus dentatum was well marked on the left side, but only a few irregularly scattered cells represented it on the right side. During life paresis of both posterior extremities and of the right anterior one were observed, which condition is stated to correspond with that met with in dogs after ablation of the right lateral lobe of the cerebellum.Google Scholar

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