From the beginning of the year 1889 to the end of 1899, 128 cases of progressive paralysis came under observation in the German Tirol; out of this number there were 104 men and 24 women. The amount of insane patients during these eleven years came to 5·4 per cent.; out-patients as well as in-patients were included in this calculation. The age at which the disease made its appearance varied between thirty and sixty-four.