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Variations in the Blood Levels of Acetoin and Butane-2:3-Diol in Normal Individuals and Mental Patients

Published online by Cambridge University Press:  08 February 2018

J. Dawson
Affiliation:
Department of Biochemistry, University of Leeds
R. P. Hullin
Affiliation:
Department of Biochemistry, University of Leeds
Arthur Pool
Affiliation:
Oldham and Rochdale Hospital Group Lately Physician Superintendent, The Retreat, York

Extract

The biochemical aspects of manic-depressive psychosis have been adequately, reviewed by McFarland and Goldstein (1939). From previous investigations, it is apparent that there is a marked alteration in carbohydrate metabolism mainly associated with a change in glucose tolerance. This phenomenon is related to alterations in emotional state and there is no suggestion that it is the cause of the mood swings which occur periodically in this type of psychosis. Apart from these variations in the control of carbohydrate metabolism, it has so far not been possible to demonstrate any changes in the blood levels of any products derived from carbohydrate metabolism.

Type
Original Articles
Copyright
Copyright © Royal College of Psychiatrists, 1954 

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