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The Treatment of Mental Defectives with Thiamine

Published online by Cambridge University Press:  08 February 2018

G. de M. Rudolf*
Affiliation:
Hortham Colony

Extract

Thiamine or aneurine has for many years been known as the anti-neuritic vitamin, although action of this substance in organic nervous trouble is not established. Less well-known is its action on the higher cerebral processes, but results of investigations appear to show that it has a definite effect on these. M. V. Dias (1947) found that the application of thiamine hydrochloride solution to the motor cortex of unanaesthetized dogs produced clonic contractions of the appropriate muscles, and Harrell (1946) reports striking psychological results on normal children.

Type
Part I.—Original Articles
Copyright
Copyright © Royal College of Psychiatrists, 1949 

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References

Bradley, C., and Green, E. (1940), Amer. J. Psychiat., 97, 388.Google Scholar
Dias, M. V. (1947), Science, 105, 211.CrossRefGoogle Scholar
Harrell, R. (1943), Contrib. to Education, 877 (Teacher's Coll., Columbia Univ.).Google Scholar
Harrell, R. (1946), J. Nutrition, 31, 283.CrossRefGoogle Scholar
Molitch, M., and Sullivan, J. P. (1937), Amer. J. Orthopsychiat., 7, 519.CrossRefGoogle Scholar
Nachmansohn, D., and Machado, A. L. (1943), J. Neurophysiol., 6, 397.Google Scholar
Nachmansohn, D. John, H. M., and Waelsch, H. (1943), J. Biol. Chem., 150, 485.Google Scholar
Price, J. C., Waelsch, H., and Putnam, T. J. (1943), J.A.M.A., 122, 1153.CrossRefGoogle Scholar
Sargant, W., and Blackburn, J. M. (1936), Lancet, ii, 1385.Google Scholar
Weil-Malherbe, H. (1936), Biochem. J., 30, 665.Google Scholar
Zimmerman, F. T., Burgomeister, B. B., and Putnam, T. J. (1946), Arch. Neur. and Psychiat., 56, 489.Google Scholar
Zimmerman, F. T., Burgomeister, B. B., and Putnam, T. J. (1947), Psychosom. Med., 9, 175.Google Scholar
Zimmerman, F. T., Burgomeister, B. B., and Putnam, T. J. (1948), Amer. J. Psychiat., 104, 593.Google Scholar
Zimmerman, F. T., and Ross, S. (1944), Arch. Neur. and Psychiat., 51, 446.Google Scholar
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