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The Relation of the Spirochæta Pallida to the Pathological Changes of Dementia Paralytica

Published online by Cambridge University Press:  19 February 2018

J. F. Smyth*
Affiliation:
West Riding Mental Hospital, Wakefield

Extract

The rationale of the malarial treatment of general paralysis has not, so far, been thoroughly understood. It has been believed by some that the remission is due to the destruction of spirochætes in the cortex by the intermittent waves of high temperature, which leave them no time to organize a defensive mechanism. This explanation assumes that the destruction of the spirochæte with, perhaps, its removal from the brain may result in a cessation of the active progress of the disease and, in some cases, in a complete return to normal cerebral function.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1928 

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