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Physiological Effects of Schizophrenic Body Fluids

Published online by Cambridge University Press:  08 February 2018

Edith G. McGeer  and
Patrick L. McGeer
Edith G. McGeer
Affiliation:
From the Department of Neurological Research, University of British Columbia, Vancouver, Canada
Patrick L. McGeer
Affiliation:
From the Department of Neurological Research, University of British Columbia, Vancouver, Canada
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Extract

Controversy has raged for over half a century as to whether schizophrenia, the most severe of all mental illnesses, could have an organic basis or whether its origin lay strictly in the psyche. Over the years, physiologists have probed into almost every aspect of the soma in the quest for some abnormality which would account for the schizophrenic syndrome. Many possibilities have been considered, investigated to a degree and then abandoned when definitive answers were not forthcoming. A dominant approach throughout has been the search for some psychotoxic material circulating in schizophrenic body fluids. Activity has been spurred by the recurrent recognition that chemical agents such as the ergot alkaloids, mescaline, bulbocapnine and lysergic acid diethylamide (LSD-25), could induce in normal persons transient mental disturbances similar to those seen in schizophrenia.

Type
Original Articles
Information
Journal of Mental Science , Volume 105 , Issue 438 , January 1959 , pp. 1 - 18
Copyright
Copyright © Royal College of Psychiatrists, 1959 

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