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The Origin and Spread of Dementia Paralytica

Published online by Cambridge University Press:  08 February 2018

E. H. Hare
E. H. Hare*
Affiliation:
Bethlem Royal and The Maudsley Hospitals
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Extract

Dementia paralytica is a declining disease. Deaths due to it in England and Wales were first recorded by the Registrar General in 1901 and since that year, when the number was 2,272, the annual figure has fallen steadily until in 1957 it was only 68. Moreover, there is evidence (adduced below) that not more than a small part of this decline can be attributed to improvements in medical treatment. The fear that there might be a recrudescence of dementia paralytica as a result of the spread of syphilis during the second world war has not so far been realized and it seems likely that what is now, in Great Britain at all events, an obsolescent disease will soon become a rarity. Yet there are many unsolved problems in its history. We do not know, for example, why the alleged references to this striking disease were so few and so inadequate until the third decade of the nineteenth century. We do not know why its recognition in many countries was so tardy in spite of the clear description given by the French alienists. Nor do we know why the disease, which at the start of the nineteenth century seems to have been predominantly one of males, has gradually—and at different rates in different countries—become much more evenly distributed between the sexes.

Type
Original Articles
Information
Journal of Mental Science , Volume 105 , Issue 440 , July 1959 , pp. 594 - 626
Copyright
Copyright © Royal College of Psychiatrists, 1959 

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References

Arieti, S., “General Paresis in Senility”, Amer. J. Psychiat., 1945, 101, 585.Google Scholar
Arnold, T., Observations on the Nature, etc. of Insanity, 1786. London.Google Scholar
Ashe, I., “Some Observations on General Paralysis”, J. Ment. Sci., 1876, 22, 82.Google Scholar
Austin, T. J., General Paralysis, its Symptoms, Causes and Seat, 1859. London.Google Scholar
Ballet, G., and Blocq, P., in Traité de Medicine, ed. by Masson, G., 1894, Vol. 6, p. 1011. Paris.Google Scholar
Baillarger, M., “Délire hypocondriaque des déments paralytiques”. Gaz. des Hôpitaux, 1857, pp. 55, 218, 477.Google Scholar
Idem , “De la découverte de la paralysie générale, I”, Ann. Méd.-Psychol., 1859, 5, 509.Google Scholar
Idem , “De la découverte de la paralysie générale, II”, ibid., 1860, 6, 1.Google Scholar
Baird, H., “Statistical Observations on General Paralysis”, J. Ment. Sci., 1905, 51, 581.CrossRefGoogle Scholar
Bayle, A. L. J., Recherches sur l'arachnitis chronique, la gastrite et la gastro-entérite chroniques, et la goutte, considerées comme les causes de l'aliénation mentale, 1822. Paris.Google Scholar
Idem , Traité des Maladies du Cerveau, 1826. Paris.Google Scholar
Berkley, H. J., “Dementia Paralytica in the Negro”, Johns Hopkins Hosp. Bull., 1893, 4, 94.Google Scholar
Idem , A Treatise on Mental Disease, 1900. New York.Google Scholar
Blandford, G. F., Insanity and its Treatment, 1871. London.Google Scholar
Bostroem, A., in Handbuch der Geisteskrankheiten, ed. by Bumke, O., 1930, Vol. 8, p. 165. Berlin.Google Scholar
Bonnet, H., and Poincaré, —., “Recherches sur l'anatomie pathologique et la nature de la paralysie générale”, Annal. Méd.-Psychol., 1868, 12 (4th series), 169.Google Scholar
Boyd, R., “Vital Statistics, etc. in the Somerset Lunatic Asylum”, J. Ment. Sci., 1865, 10, 491.Google Scholar
Browne, W. A. F., “New Cerebro-psychical Diseases”, Amer. J. Insan., 1875, 32, 198.Google Scholar
Bucknill, J. C., “The Diagnosis of Insanity”, J. Ment. Sci., 1857, 3, 141.Google Scholar
Idem and Tuke, D. H., A Manual of Psychological Medicine, 1858, p. 17. London.Google Scholar
Idem , ibid., 1874, 3rd edition. London.Google Scholar
Bullen, F. St.J., “Inquiries into a Variation of Type in General Paralysis”, J. Ment. Sci., 1893, 39, 185.CrossRefGoogle Scholar
Burrows, G. M., Commentaries on the Causes, etc. of Insanity, 1829. London.Google Scholar
Calmeil, L. F., De la Paralysie considérée chez les Aliénés, 1826. Paris.Google Scholar
Idem , Traité des Maladies Inflammatoires du Cerveau, 1859. Paris.Google Scholar
Cantarow, A., and Trumper, M., Lead Poisoning, 1944. Baltimore, p. vii.Google Scholar
Castiglioni, A., A History of Medicine, 1947. 2nd edition. Translated by Krumbhaar, E. B. New York.Google Scholar
Chase, R. H., General Paresis, 1902. London.Google Scholar
Clouston, T. S., Clinical Lectures on Mental Diseases, 1883. London.CrossRefGoogle Scholar
Idem , ibid., 1904. 6th edition. London.Google Scholar
Conolly, J., An Inquiry concerning the Indications of Insanity, 1830. London.Google Scholar
Idem , On Some Forms of Insanity, 1849. London.Google Scholar
Cullen, W., Synopsis Nosologiae Methodicae, 1769. Edinburgh.Google Scholar
Dayton, N. A., New Facts on Mental Disorders, 1940. Illinois.CrossRefGoogle Scholar
Deas, P. M., “Five Years of Statistics, etc.”, J. Ment. Sci., 1879, 25, 8.Google Scholar
Diefendorf, A. R., “The Etiology of Dementia Paralytica”, Brit. med. J., 1906, ii, 744.Google Scholar
Ellis, W. C., A Treatise on the Nature, etc. of Insanity, 1838. London.Google Scholar
Esmarch, F., and Jessen, W., “Syphilis und Geistesstöring”, Allg. Ztschr. f. Psychiat., 1857, 14, 20.Google Scholar
Esquirol, E., Article on “Dementia” in the Dictionnaire des Sciences Médicales, 1814.Google Scholar
Idem , Des Maladies Mentales, 1838. Paris.Google Scholar
Falret, J., Recherches sur la Folie Paralytique, 1853. Paris.Google Scholar
Froshang, H., and Ytrehus, A., “A Study of General Paralysis with special reference to the Reasons for the Admission of these Patients to Hospital”, Acta Psychiat. Neurol. Scand., 1956, 31, 35.Google Scholar
Garrison, F. H., An Introduction to the History of Medicine, 1929. 4th edition. London.Google Scholar
Georget, E. J., De la Folie, 1820. Paris.Google Scholar
Green, E. M., “Psychosis among Negroes—a Comparative Study”, J. nerv. ment. Dis., 1914, 41, 697.CrossRefGoogle Scholar
Griesinger, W., Mental Pathology and Therapeutics, 1861. Translated in 1867 by Robertson, C. L., and Rutherford, J., London.Google Scholar
Guthrie, D., A History of Medicine, 1945. London.Google Scholar
Guthrie, L. G., “ ‘Myasthenia Gravis' in the Seventeenth Century”, Lancet, 1903, i, 330.Google Scholar
Haslam, J., Observations on Insanity, 1798. London.Google Scholar
Idem , Observations on Madness and Melancholy, 1809. London.Google Scholar
Heiberg, P., “Variations in the Number of Reported Cases of Syphilis and in the Number of Deaths from General Paresis”, Acta Psychiat. Neurol. Scand., 1932, 7, 189.Google Scholar
Hirsch, A., Handbook of Geographical and Historical Pathology, 1885. London. Vol. 2, Ch. 2. Translation from the 2nd edition by Creighton, C.Google Scholar
Hutton, E. L., “Recent Advances in the Aetiology and Treatment of Neurosyphilis”, J. Ment. Sci., 1941, 87, 1.Google Scholar
Hyslop, T. B., “Pseudo-General Paralysis”, ibid., 1896, 42, 303.Google Scholar
Idanoff, I. D., “De la Paralysie Générale chez la femme”, Annal. Méd.-Psychol., 1894, 19, 382.Google Scholar
Iskrant, A. P., “The Economic Cost of Paresis in the United States”, J. ven. Dis. Inf., 1945, 26, 175.Google Scholar
Journal of Mental Science, Discussion on “The Causation of General Paralysis”, 1873, 19, 164.Google Scholar
Ibid, Review of the 36th Annual Report of the General Board of Commissioners in Lunacy for Scotland, 1895, 41, 116.Google Scholar
Ibid, Discussion on “Pseudo-General Paralysis”, 1896, 42, 646.Google Scholar
Ibid, Review of the 48th Annual Report of the General Board of Commissioners in Lunacy for Scotland, 1907, 53, 154.Google Scholar
King, A., “These Dying Diseases’; Venereology in Decline?”, Lancet, 1958, i, 651.Google Scholar
Klotz, O., “Concerning Aneurysms”, 3rd Gordon Bell Memorial Lecture, University of Toronto Studies, Pathological Series (quoted by Rolleston, 1927b), 1926.Google Scholar
Kojog, F., “Die endemische Syphilis in Bosnia und Herzegowina”, Dermatologica, 1939, 79, 361.Google Scholar
Kraepelin, E., “General Paresis”, Nervous and Mental Diseases Monograph No. 14, 1913. New York. Translated by Moore, J. W.Google Scholar
Idem , “The Problems presented by General Paresis”, J. nerv. ment. Dis., 1926, 63, 209.Google Scholar
Idem , Psychiatrie, 1927. 9th edition. Vol. 2. Leipzig.Google Scholar
Krafft-Ebing, R. von, “Zur Geschichte und Literatur der Dementia Paralytica”, Zeitschr. f. Psychiat., 1866, 23, 627.Google Scholar
Idem , Die Progressive Allgemeine Paralyse, 1894. Vienna.Google Scholar
Lancet , “A new disease?”, 1957, ii, 285.Google Scholar
Lees, R., “Syphilis—a historical and modern problem”, Trans. Med.-Chir. Soc. Edin., 1950, 129, 58.Google Scholar
Leigh, D., “John Haslam, M.D., 1764–1844, Apothecary to Bethlem”, J. Hist. Med., 1955, 10, 17.Google Scholar
Lennox, W. G., “Neurosyphilis among the Chinese”, Arch. Neurol. Psychiat., 1923, 9, 26.Google Scholar
Lomholt, M., “Clinic and Prognosis of Malaria-treated Paralysis”, Acta Psychiat. Neurol. Scand., 1944, Suppl. 30.Google Scholar
Lunier, M. L., “Recherches sur la paralysie générale progressive”, Annal. Méd.-Psychol., 1849, p. 183.Google Scholar
McCartney, J. L., “Why is Neurosyphilis uncommon in the Tropics?”, Mil. Surgeon, 1946, 99, 21.Google Scholar
MacDonald, A. E., “General Paresis”, Amer. J. Insan., 1877, 33, 451.Google Scholar
Major, R. H., A History of Medicine, 1954. Oxford.Google Scholar
Malzberg, B., “Mental Disease in Negroes in New York State, 1939–41”, Ment. Hyg., 1953, 37, 450.Google Scholar
Marie, M. A., in La Paralysie Générale, Centenaire de la Thèse de Bayle, 1922. Vol. 2, p. 139. Paris.Google Scholar
Maudsley, H., The Physiology and Pathology of Mind, 1867. London.Google Scholar
Idem , The Pathology of Mind, 1879. London.Google Scholar
Idem , ibid., 1895, 2nd edition. London.Google Scholar
Meryon, E., Practical and Pathological Researches on the Various Forms of Paralysis, 1864. London, p. 153.Google Scholar
Mettler, C. C., A History of Medicine, 1947. Philadelphia.Google Scholar
Meyer, A. “A Note on the Concept of Dementia Paralytica at the time of Robert Schumann's death in 1856”, J. Ment. Sci., 1959, 105, 116.Google Scholar
Mickle, W. J., General Paralysis of the Insane, 1880. London.Google Scholar
Idem , ibid., 1886. 2nd edition. London.Google Scholar
Millingen, , J. G., Aphorisms on the Treatment and Management of the Insane, 1840. London, p. 46.Google Scholar
Mönkemüller, —., “Zur Geschichte der progressiven Paralyse”, Zeit. f. d. ges. Neurol. Psychiat., 1911, 5, 500.Google Scholar
Moore, M., and Solomon, H. C., “Contributions of Haslam, Bayle and Esmarch and Jessen to the history of Neurosyphilis”, Arch. Neurol. Psychiat., 1934, 32, 804.Google Scholar
Moreira, J., and Penafiel, A., “Contributions to the Study of Dementia Paralytica in Brazil”, J. Ment. Sci., 1907, 53, 507.Google Scholar
Morris, H., “Observations on the History of Syphilis”, Lancet, 1912, ii, 497.Google Scholar
Morton, L. T., Garrison and Morton's Medical Bibliography, 1954. 2nd edition. London, p. 418.Google Scholar
Mott, F. W., Arch. Neurol. (London), 1900, 1, 166.Google Scholar
Idem , “Recent developments in our knowledge of Syphilis in relation to Diseases of the Nervous System”, Brit. med. J., 1908, i, 10.Google Scholar
Neumann, H., Lehrbuch der Psychiatrie, 1859. Quoted by Krafft-Ebing, 1894.Google Scholar
Nicole, J. E., “Malaria in Neurosyphilis, 1923–1943”, J. Ment. Sci., 1943, 89, 381.Google Scholar
Nonne, M., Syphilis und Nervensystem, 1902. Berlin, p. 543. Quoted by Zilboorg and Henry, 1941.Google Scholar
Padget, P., and Moore, J. E., “Syphilis, a review of the recent Literature”, Arch. int. Med., 1936, 58, 901.Google Scholar
Pinel, P., Nosographie Philosophique ou Méthode de l'Analyse appliquée à la Médecine, 1798. Paris.Google Scholar
Idem , Traité Médico-philosophique sur l'Aliénation Mentale, 1809. 2nd edition. Paris.Google Scholar
Plaut, F., Paralysestudien bei Negern und Indianern, 1926. Berlin, p. 25.Google Scholar
Power, T. D., “The Aetiology of General Paralysis of the Insane”, J. Ment. Sci., 1930, 76, 524.Google Scholar
Prichard, J. C., A Treatise on Insanity, 1835. London.Google Scholar
Report together with the Minutes of Evidence and an Appendix of Papers from the Committee appointed to consider of Provision being made for the better Regulation of Madhouses in England (1815). London.Google Scholar
Richardson, , Prichard, J. C., “Asylum Reports for 1890”, J. Ment. Sci., 1891, 37, 604.Google Scholar
Robertson, G. M., “The Discovery of General Paralysis”, ibid., 1923, 69, 1.Google Scholar
Rolleston, H., “Changes in the Clinical Aspects of Disease”, Brit. med. J., 1927a, i, 87.Google Scholar
Idem , “Clinical Variations in Disease from the Historical Point of View”, ibid., 1927b, ii, 205.Google Scholar
Rosanoff, A. J., Manual of Psychiatry, 1938. 7th edition. New York, p. 341.Google Scholar
Salomon, E., “On the Pathological Elements of General Paresis”, J. Ment. Sci., 1862, 8, 365.Google Scholar
Samuels, W. F., “General Paralysis of the Insane in the Federated Malay States”, ibid., 1916, 62, 411.Google Scholar
Sander, W., “Die paralytische Geistesstörung beim weiblichen Geschlecht”, Berlin Klin. Woch., 1870, 7, 81.Google Scholar
Sankey, W. H. O., “The Pathology of General Paralysis”, J. Ment. Sci., 1864, 9, 467.Google Scholar
Idem , Lectures on Mental Diseases, 1866. London.Google Scholar
Semelaigne, R., Les Grands Aliénistes Français, 1894. Paris.Google Scholar
Idem , Les Pionniers de la Psychiatrie Française, 1930. Paris.Google Scholar
Skae, D., “Contributions to the Natural History of General Paralysis”, Edinburgh med. J., 1860, 5, 885.Google Scholar
Smith, J. C., “Notes on the Appearance of Dementia Paralytica and the relation between its Frequency and the Antisyphilitic Treatment”, Acta Psychiat. Neurol. Scand., 1926, 1, 346.Google Scholar
Spitzka, E. C., Insanity, its Classification, Diagnosis and Treatment, 1883. New York.Google Scholar
Stewart, R. M., “General Paralysis; its unsolved problems”, J. Ment. Sci., 1924, 70, 33.Google Scholar
Stewart, R. S., “The Increase of General Paralysis in England and Wales; its Causation and Significance”, ibid., 1896, 42, 760.Google Scholar
Idem , “Decrease of General Paralysis of the Insane in England and Wales”, ibid., 1901, 47, 41.Google Scholar
Stoddart, W. H. B., Mind and its Disorders, 1921. 4th edition. London.Google Scholar
Sudhoff, K., Essays in the History of Medicine, 1926. New York, Ch. 22, p. 259.Google Scholar
Toulouse, E., in La Paralysie Générale, Centenaire de la Thèse de Bayle, 1922. Paris, Vol. 2, p. 11.Google Scholar
Tuke, , Harrington, , “On General Paralysis”, J. Ment. Sci., 1859, 5, 575 and 6, 200.CrossRefGoogle Scholar
Wagner, C. C., “The Comparative Frequency of General Paresis”, Amer. J. Insan., 1902, 58, 587.Google Scholar
Walshe, F. M. R., Diseases of the Nervous System, 1947. 5th edition. Edinburgh.Google Scholar
Westphal, C., “On the present state of our knowledge regarding General Paralysis of the Insane”, J. Ment. Sci., 1868, 14, 162.Google Scholar
Whitwell, J. R., Syphilis in Earlier Days, 1940. London.Google Scholar
Willis, T., De Anima Brutorum, 1672. Translated in Dr. Willis' Practice of Physick, by Samuel Pordage, London, 1684. Part II, “Concerning the Soul of the Brutes”, Ch. 9, et seq. Google Scholar
Wilson, J. H., on “General Paralysis of the Insane”, Liverpool Med.-Chir. J., 1857, p. 231.Google Scholar
Wilson, S. A. K., Neurology, 1941. 2nd edition, 1954, edited by A. N. Bruce, London.Google Scholar
Wise, —., “General Paralysis of the Insane”, Indian med. Gaz., 1869, 4, 75.Google Scholar
Workman, J., “Pathological Notes”, Amer. J. Insan., 1858, 15, 1.Google Scholar
Idem , “On Paresis”, Canada Lancet, 1878, 10, 357 and 11, 1.Google Scholar
Zilboorg, C., and Henry, G. W., A History of Medical Psychology, 1941. London, Ch. 13.Google Scholar
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