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On the Nature of Inhibition: a Review.∗

Published online by Cambridge University Press:  19 February 2018

W. R. Ashby
W. R. Ashby*
Affiliation:
Leavesden Mental Hospital
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Extract

While, during the last thirty years, great advances have been made in our knowledge of inhibition, its properties and its interactions with excitation, yet little progress has been made in elucidating the precise nature of inhibition itself. Pavlov (67), for instance, has discovered many of the principles of inhibition, its interaction with excitation, its irradiation, its extinction and so on. But all the time he is dealing with inhibition simply as a phenomenon which shows itself in the end-reaction. With regard to what is actually happening in the cortex, he admits that it is unknown. Yet the phenomenon of inhibition is one of prime importance in the organization of the central nervous system. Perhaps, at times, while watching, say, a dog chasing a ball, one is apt to forget the many reactions which are not happening in one's interest in what is happening. Yet an overdose of strychnine to the dog will soon remind one that every movement of each limb, every twitch of a muscle is surrounded, as it were, by a wall of inhibition, checking, controlling and timing so as to produce the final smooth and graceful co-ordination.

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 80 , Issue 329 , April 1934 , pp. 198 - 222
Copyright
Copyright © Royal College of Psychiatrists, 1934 

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References

1 Adie, W. J., “Narcolepsy”, Brain, 1926, xlix, p. 257.Google Scholar
2 Adrian, E. D., The Basis of Sensation, London, 1928.Google Scholar
3 Adrian, E. D., Brain, 1918, xli, p. 23.CrossRefGoogle Scholar
4 Adrian, E. D., quoted in (78).Google Scholar
5 Adrian, E. D. and Bronk, D. W., Journ. Physiol., 1929, lxvii, p. 119.Google Scholar
6 Anrep, V. von, and Cybulski, N., quoted in (11).Google Scholar
7 Ashby, W. R., Journ. of Neur. and Psychopath., 1931, xii, p. 148.Google Scholar
8 Asher, , Zeitschr. f. Biol., 1909, lii, p. 311.Google Scholar
9 Bayliss, W. M., Journ. Physiol., 1893, xiv, p. 303.Google Scholar
10 Bayliss, W. M., Interfacial Forces and Phenomena in Physiology, London, 1923.Google Scholar
11 Bayliss, W. M., Principles of General Physiology, fourth edition, London, 1924.Google Scholar
12 Bayliss, W. M., Proc. Roy. Soc. Lond., 1908, lxxx, b, p. 339.Google Scholar
13 Bayliss, W. M., Journ. Physiol., 1893, xiv, p. 303.Google Scholar
14 Biedermann, W., Pflüger's Arch., 1900, lxxx.Google Scholar
15 Bayliss, W. M., Sitzb. d. Akad. d. Wiss., Wien, 1887, xciii, p. 8.Google Scholar
16 Bok, S. T., Folia neurobiologica, 1915, ix, p. 475.Google Scholar
17 Bourguignon, G., Nouveau traité de médecine, Paris, fasc. xviii, p. 521.Google Scholar
18 Bayliss, W. M., La Chronaxie chez l'homme, Paris, 1923.Google Scholar
19 Bowditch, and Warren, , Journ. Physiol., 1886, vii, p. 439.Google Scholar
20 Briggs, I. G., Epilepsy, Hysteria and Neurasthenia, London, 1921.Google Scholar
21 Brinkman, and Van Dam, , Pfliiger's Arch., 1922, cxcvi, p. 66.Google Scholar
22 Brunton, T. L., “On the Nature of Inhibition”, Nature, 1883, xxvii, pp. 419, 436, 467, 485.Google Scholar
23 Cajal, S. Ramon, Y., Histologie du syst me nerveux, Paris, 1909 (Translation: Histology of the Nervous System, London, 1932).Google Scholar
24 Cannon, W. B., Bodily Changes in Pain, Hunger, Fear and Rage, New York, 1915.Google Scholar
25 Child, C. M., Physiological Foundations of Behaviour, New York, 1924.Google Scholar
26 Child, C. M., The Origin and Development of the Nervous System from a Physiological Viewpoint, Chicago, 1921.Google Scholar
27 Coghill, G. E., Journ. Comp. Neurol., 1924, xxxvii, p. 37.Google Scholar
28 Coghill, G. E., Anatomy and the Problem of Behaviour, Cambridge, 1929.Google Scholar
29 Cyon von, , quoted in (45).Google Scholar
30 Dale, and Evans, , Journ. Physiol., 1922, lvi, p. 125.Google Scholar
31 Dale, H. H., ibid., 1914, xlviii, p. 3.Google Scholar
32 Davis, , Forbes, , Brunswick, and Hopkins, , Amer. Journ. Physiol., 1926, lxxvi, p. 448.CrossRefGoogle Scholar
33 Demole, , Rev. Neurol., 1927, xxxiv, p. 850.Google Scholar
34 Dixon, W. E., Manual of Pharmacology, fifth edition, London, 1923.Google Scholar
35 Eccles, J. C., and Sherrington, C. S., Proc. Roy. Soc. Lond., 1931, cxvii, B, p. 597.Google Scholar
36 Economo, C. von, Rev. Neurol., 1927, xxxiv, p. 837.Google Scholar
37 Erlanger, , Amer. Journ. Physiol., 1905, xiii, p. 372.Google Scholar
38 Fearing, F., Reflex Action, London, 1930.Google Scholar
39 Forbes, A., Quart. Journ. Exper. Physiol., 1912, v, p. 149.Google Scholar
40 Frey, M. von, “Über die Wirkungsweise der erschlaffenden Gefässnerven”, Ludwig's Arbeiten, 1876, xi, p. 89.Google Scholar
41 Fulton, J. F., Muscular Contraction and Reflex Control of Movement, Baltimore, 1926.Google Scholar
42 Gotch, F., and Burch, G. J., Phil. Trans. 1896, clxxxvii, p. 347.Google Scholar
43 Harrison, and Braus, (quoted in Uexküll, ), Theoretical Biology, London, 1926.Google Scholar
44 Head, H., and Holmes, G., Brain, 1911, xxxiv, p. 109.Google Scholar
45 Hering, H. E., Ergebn. d. Physiol., 1902.Google Scholar
46 Howell, W. H., “Inhibition” Physiol. Rev., 1925, v, p. 161.Google Scholar
47 Howell, W. H., Amer. Journ. Physiol., 1905, xv, p. 280.Google Scholar
48 Howell, W. H. and Duke, W. W., ibid., 1908, xxi, p. 51.Google Scholar
49 Ingvar, S., Proc. Amer. Soc. Exp. Biol, and Med., 1920, xvii, p. 198.Google Scholar
50 James, W., Boston Soc. of Nat. Hist., 1880.Google Scholar
51 Kato, , The Theory of Decrementless Conduction, Tokio, 1924.Google Scholar
52 Langley, J. N., Journ. Physiol., 1898, xxiii, p. 240.Google Scholar
53 Langley, J. N., ibid., 1904, xxx, p. 439.Google Scholar
54 Lapicque, L., “Chronaxy Switching in the Nervous System”, Science, 1929, lxx, p. 151.Google Scholar
55 Lapicque, L., Rev. génér. des sciences, 1910, xxi, p. 113.Google Scholar
56 Lashley, K. S., “Basal Neural Mechanisms in Behaviour”, Psychol. Rev., 1930, xxxvii, p. 1.Google Scholar
57 Loewi, , Pflüger'sArch., 1921, clxxxix, p. 239.Google Scholar
58 Loewi, , ibid., 1922, cxciii, p. 201.Google Scholar
59 Lucas, K., The Conduction of the Nervous Impulse, 1917.Google Scholar
60 Macdonald, J. S., Proc. Roy. Soc. Lond., 1905, lxxvi, B, p. 322.Google Scholar
61 McDougall, W., Brain, 1903, xxyi, p. 153.Google Scholar
62 McDougall, W., Physiological Psychology, third edition, London, 1911.Google Scholar
63 Maclean, H., Lecithin and Allied Substances, London, 1918.Google Scholar
64 McWilliam, J. A., Journ. Physiol., 1885, vi, pp. 16, 192.Google Scholar
65 Mangold, E., Zeitschr. allgem. Physiol., 1905, v, p. 135.Google Scholar
66 Pavlov, I. P., “The Identity of Inhibition with Sleep and Hypnosis”, Sei. Mo., 1923, xvii, p. 603.Google Scholar
67 Pavlov, I. P., Conditioned Reflexes, London, 1927.Google Scholar
68 Pavlov, I. P., “La vraie physiologie cérébrale”, Arch. Internat, de Physiol., 1921, xviii, p. 607.Google Scholar
69 Pick, E., Wien. klin. Wochenschr., 1927, xl, p. 1.Google Scholar
70 Piotrowski, G., Journ. Physiol., 1893, xiv, p. 163.Google Scholar
71 Reid, H., Amer. Journ. Physiol., 1918, xlv, p. 197.Google Scholar
72 Richet, C., Physiol, d. muscles et d. nervs., Paris, 1882.Google Scholar
73 Rogers, C. G., Textbook of Comparative Physiology, New York, 1927.Google Scholar
74 Romanes, J., Phil. Trans. Roy. Soc. Lond., 1877, clvii.Google Scholar
75 Schafer, , The Endocrine Organs, 1924.Google Scholar
76 Sherrington, C. S., The Integrative Action of the Nervous System, New Haven, 1926.Google Scholar
77 Sherrington, C. S. and Sowton, S. C. M., Journ. Physiol., 1911, xlii, p. 383.CrossRefGoogle Scholar
78 Sherrington, C. S., Proc. Roy. Soc. Lond., 1925, xcvii, B, p. 519.Google Scholar
79 Sherrington, C. S., ibid., 1908, lxxx, B, p. 565.Google Scholar
80 Sherrington, C. S., Brit. Assoc. Reports, Pres. Add., Sect. I, 1904.Google Scholar
81 Verworn, M., Irritability, New Haven, 1913.Google Scholar
82 Verworn, M., General Physiology.— (83) Wedensky, Pflüger's Arch., 1903, c, p. 1.Google Scholar
84 Wilson, S. A. K., Proc. Roy. Soc. Med., 1930, xxiv, p. 1.Google Scholar
85 Worrall, R. L., “The Cerebral Cortex in Unconsciousness”, Journ. of Neur. and Psychopath., 1931, xi, p. 328.CrossRefGoogle Scholar
86 Wright, S., Applied Physiology, London, 1931.Google Scholar
87 Wundt, W., Über d. Reflex Vorgang u. d. Wesen d. central. Innervation, Stuttgart, 1876.Google Scholar
88 Wundt, W., Grundzüge der Physiol. Psychol., 1880.Google Scholar
89 Hunt, , Journ. Exp. Med., 1897, ii, p. 151.Google Scholar
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