The study of the intermissions which occur in the course of general paralysis is not the least interesting chapter in the history of this disease. Is it not a matter of surprise, that an affection which occasions such grave disturbances of the cerebral organ should undergo ameliorations so pronounced as might well be taken for a real cure, did not the experience of each day teach us that it is but arrested for a longer or shorter time, and that sooner or later the paralysis resumes its fatal course. Have not even alienists asserted that they have cured demented paralytics ? The existence of intermission in the course of general paralysis does not at the present time need to be demonstrated. It is enough to glance at the treatises of MM. Calmeil and Bayle, to find the most remarkable examples of it.