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Measurements of Effects of Hyaluronidase in Insulin Coma Treatment
Published online by Cambridge University Press: 08 February 2018
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Hyaluronidase, the “spreading factor” is widely used today to aid the distribution and absorption of fluids injected at various sites into body tissues. It is derived from the head of the male sperm cell which by its action dissolves hyaluronic acid in the “shell” surrounding the female egg cell and thereby allows spermal penetration and conception; generally speaking it dissolves the ground substance between cells. The most remarkable usage is in paediatrics where it allows for quick replacement of lost fluid and salt in gastro-enteritis, obviating the need to find veins, and thereby saving practically all cases from death by dehydration. There are many other uses.
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- Copyright © Royal College of Psychiatrists, 1958
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