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Imipramine with electrical treatment in depression—A controlled trial

Published online by Cambridge University Press:  08 February 2018

C. P. Seager
Affiliation:
Barrow Hospital, Bristol
R. L. Bird
Affiliation:
Barrow Hospital

Extract

Since the introduction of anti-depressant drugs into general use in the psychiatric field, there have been several statements to the effect that such a drug administered concurrently with electrical treatment reduces the number of shocks required to achieve a satisfactory response. This has been claimed by Sargant (1961) but without experimental support. Dunlop (1960) has published a comparison between the number of electrical treatments given with the anti-depressant drug during a particular attack, and the number of treatments without the aid of a drug in an earlier attack in the same patient: however, comparison of treatments in the same group of patients at different times is unreliable because there may be other factors to account for the differences noted. A controlled trial is necessary to ensure that all factors are constant other than the one under consideration.

Type
Therapeutic Trials
Copyright
Copyright © Royal College of Psychiatrists, 1962 

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References

Dunlop, E. (1960). Dis. Nerv. Syst., 21, 130.Google Scholar
Kiloh, , et al (1960). J. Ment. Sci., 106, 1139.CrossRefGoogle Scholar
Muller, D. (1961). J. Ment. Sci., 107, 994.CrossRefGoogle Scholar
Sargant, W. (1961). Brit. Med. J., i, 225.CrossRefGoogle Scholar
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