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The Effects of Ethyl Alcohol on Maze Behaviour and Motor Co-Ordination of Rats. 2. the Assessment of Degrees of Intoxication

Published online by Cambridge University Press:  08 February 2018

Leslie D. MacLeod
Leslie D. MacLeod*
Affiliation:
Burden Neurological Institute, Bristol
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Extract

A previous communication (Carpenter and MacLeod, 1952) described the application of a maze, together with a simple test of limb co-ordination, to the study of alcoholic intoxication in rats, as modified by acetaldehyde. As part of a scheme of work here, it was desired to observe the effect of drugs and other substances upon the degree of intoxication produced in rats by ethyl alcohol. Such studies, pursued by the methods previously given, soon led to a formidable mass of recorded material, some features of which were not adequately dealt with by the scoring technique employed. It became necessary to adopt a scoring system which would give an overall indication of the various manifestations of alcoholic intoxication, to serve for the purpose of compact tabulation of results and the drawing of conclusions.

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 99 , Issue 415 , April 1953 , pp. 295 - 300
Copyright
Copyright © Royal College of Psychiatrists, 1953 

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References

Carpenter, R. K., and MacLeod, L. D., J. Ment. Sci., 1952, 98, 167.CrossRefGoogle Scholar
Warden, Jenkins and Warner, , Comparative Psychology. I. Principles and Methods, 1935. New York: Ronald Press.Google Scholar
Kreezer, G. L., in The Rat in Laboratory Investigation, ed. Farris, E. J. and Griffith, J. Q., 2nd ed., 1949. London: Lippincott.Google Scholar
Mather, K., Statistical Analysis in Biology, 3rd. ed., 1949. London: Methuen.Google Scholar
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