In a previous paper we described the lesions in the posterior columns of the spinal cord in cases of general paralysis, and pointed out their similarity with those in early tabes dorsalis. We showed that the degeneration always commenced at the point where the posterior roots enter the cord. It is here that the sensory fibres become part of the central nervous system and lose their neurilemma sheath; and in all cases we found that precisely at this point degeneration began.