The object of this paper is to set out briefly some of the chief clinical points observed during an epidemic of dysentery at the Devon County Asylum, as the treatment of this disease still leaves much to be desired with a mortality of nearly 1 in 5 for all asylums in England. The epidemic started two years ago, and although the number of cases has much diminished during the past few months, there are as yet no certain indications that the epidemic is drawing to an end. Personally I have only seen those cases which have occurred since October, 1909, i.e., 142 in a period of twelve months.