Hostname: page-component-78c5997874-8bhkd Total loading time: 0 Render date: 2024-11-05T11:23:31.077Z Has data issue: false hasContentIssue false

A Central Homeostatic Mechanism in Schizophrenia

Published online by Cambridge University Press:  08 February 2018

Denis Hill
Affiliation:
Department of Clinical Neurophysiology, Institute of Psychiatry, Maudsley Hospital, London
J. Theobald
Affiliation:
Department of Clinical Neurophysiology, Institute of Psychiatry, Maudsley Hospital, London
Marion Waddell
Affiliation:
Department of Clinical Neurophysiology, Institute of Psychiatry, Maudsley Hospital, London

Extract

The condition of physiological homeostasis results from the maintenance of a steady state for the functions of organs and the levels of different blood constituents, despite the constant variability of other factors from without and within tending to upset that steady state. Most organs of the body show variability and adjustment of their functions in the presence of stresses, but the brain cannot itself make such adjustments. Yet any change in the external or internal environment of the body affects the brain, and particularly the cortex, most severely. Homeostatic mechanisms function as defensive mechanisms, protecting the cortex of the brain from harmful alterations in the internal environment.

Type
Part I.—Original Articles
Copyright
Copyright © Royal College of Psychiatrists, 1951 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Cohen, L. H., and Fierman, J. H. (1938), Endocrinol., 22, 548.Google Scholar
Finkelman, I., and Stevens, W. M. (1936), J. Neurol. and Psychopath., 16, 321.Google Scholar
Freeman, H., and Carmichael, H. T. (1935), Arch. Neurol, and Psychiat., 33, 342.Google Scholar
Idem and Rodnick, E. H. (1940), Psychosom. Med., 2, 101.Google Scholar
Gellhorn, E. (1942), Autonomic Regulations. New York.Google Scholar
Hoskins, R. G. (1946), The Biology of Schizophrenia. London.Google Scholar
Idem and Sleeper, F. H. (1930), Am. J. Psychiat., 10, 411.Google Scholar
Jung, R., and Carmichael, E. A. (1938), Arch, of Psychiat., 107, 300.Google Scholar
Linton, J. M., Hamelink, M. H., and Hoskins, R. G. (1934), Arch. Neurol. and Psychiat., 32, 712.Google Scholar
Miller, W. R. (1936), J. Nerv. and Ment. Dis., 84, 418.Google Scholar
Myerson, A., Loman, J., and Damashek, W. (1937), Am. J. Ment. Sci., 193, 198.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.