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Spray Performances and Cryogenic Characteristics of C02 Snow under Cryosurgery Guided by Endoscopic

Published online by Cambridge University Press:  22 May 2014

T.-C. Lin*
Affiliation:
Research and Services Headquarters, National Cheng Kung University, Tainan, Taiwan 70101, R.O.C.
Y.-J. Shen
Affiliation:
Department of Aeronautics and Astronautics, National Cheng Kung UniversityTainan, Taiwan 70101, R.O.C.
M.-R. Wang
Affiliation:
Department of Aeronautics and Astronautics, National Cheng Kung UniversityTainan, Taiwan 70101, R.O.C.
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Abstract

This research experimentally investigated effects of injection pressure, formation chamber and bypass flow on spray performances and cryogenic characteristics of CO2 snow under cryosurgery guided by endoscopic. Results show that CO2 snow has a superior freezing capability in the application of cryosurgery. The length of formation chamber is an effective design parameter to control spray performances and cryogenic characteristics. Increase in the length of formation chamber can increase snow size and conversion ratio, as well as the cooling rate and impact area of the tissue. Thus, it is suitable for the application on wider range nidus. Moreover, the bypass flow can efficiently modulate the cooling effect of the main flow with CO2 snow particles, and extend the operation time of cryosurgery. The experimental results also show that decrease the cylinder pressure, decrease the length of formation chamber, and increase the diameter of bypass apertures can slow down the flying velocity of CO2 snow which are effective methods to control the jet velocity and prevent the risk of penetration.

Type
Research Article
Copyright
Copyright © The Society of Theoretical and Applied Mechanics, R.O.C. 2014 

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References

REFERENCES

1.Cansell, F., Aymonier, C. and Loppinet-Serani, A., “Review on Materials Science and Supercritical Fluids,Current Opinion in Solid State and Material Science, 7, pp. 331340 (2003).CrossRefGoogle Scholar
2.King, J. W. and Williams, L. L., “Utilization of Critical Fluids in Processing Semiconductors and Their Related Materials,Current Opinion in Solid State & Materials Science, 7, pp. 413424 (2003).CrossRefGoogle Scholar
3.Pettersen, J., “Flow Vaporization of CO2 in Micro-channel Tubes,Experiments Thermal Fluid Sciences, 28, pp. 111121 (2004).CrossRefGoogle Scholar
4.Ducoulombier, M., Colasson, S., Bonjour, J. and Haberschill, P., “Carbon Dioxide Flow Boiling in a Single Microchannel - Part II: Heat Transfer,Experiments Thermal Fluid Sciences, 35, pp. 597611 (2011).CrossRefGoogle Scholar
5.Ducoulombier, M., Colasson, S., Bonjour, J. and Haberschill, P., “Carbon Dioxide Flow Boiling in a Single Microchannel - Part I: Pressure Drops,Experiments Thermal Fluid Sciences, 35, pp. 581596 (2011).CrossRefGoogle Scholar
6.Shen, Y. J., Lin, T. C. and Wang, M. R., “Production of Carbon Dioxide Snow by Flash-Atomization for Material Cleaning Process,Advanced Materials Research, 569, pp. 282285 (2012).CrossRefGoogle Scholar
7.Beak, S. and Jeong, S., “Experimental Approach to Suppress Two-Phase Flow in Cryogenic Liquid Transfer Process with the Inverted U-Bend Pipe,Experiments Thermal Fluid Sciences, 42, pp. 116124 (2012).CrossRefGoogle Scholar
8.Weibel, G. L. and Ober, C. K., “An Overview of Supercritical CO2 Applications in Microelectronics Processing,Microelectronic Engineering, 65, pp. 145152 (2003).CrossRefGoogle Scholar
9.Wang, C. W., Chang, W. K., Lin, W. K., Lin, R. D., Liang, M. T., Yang, J. F. and Wang, J. B., “Supercritical CO2 Fluid for Chip Resistor Cleaning,Journal of The Electrochemical Society, 146(9), pp. 34853488 (1999).CrossRefGoogle Scholar
10.Yang, X., Xu, Z. and Zhang, C., “Molecular Dynamics Simulation of Dense Carbon Dioxide Fluid on Amorphous Silica Surfaces,Journal of Colloid and Interface Science, 297, pp. 3844 (2006).CrossRefGoogle ScholarPubMed
11.Jones, C. A. III, et al., “Applications of Dry Processing in the Microelectronics Industry Using Carbon Dioxide,Critical Reviews in Solid State and Materials Sciences, 29, pp. 97109 (2004).CrossRefGoogle Scholar
12.Hoening, S. A., “Cleaning Surfaces with Dry Ice,Compressed Air Magazine, 91, pp. 2225 (1986).Google Scholar
13.Sherman, R., “Carbon Dioxide Snow Cleaning,Particulate Science and Technology, 25, pp. 3757 (2007).CrossRefGoogle Scholar
14.Sherman, R., Hirt, D. and Vane, R., “Surface Cleaning with the Carbon Dioxide Snow Jet,Journal of Vacuum Science & Technology A, 12, pp. 18761881 (1994).CrossRefGoogle Scholar
15.Liu, Y. H., Maruyama, H. and Matsusaka, S., “Effect of Particle Impact on Surface Cleaning Using Dry Ice Jet,Aerosol Science and Technology, 45, pp. 15191527 (2011).CrossRefGoogle Scholar
16.Yang, S. C., Huang, K. S. and Lin, Y. C., “Optimization of a Pulsed Carbon Dioxide Snow Jet for Cleaning CMOS Image Sensors by Using the Taguchi Method,Sensors and Actuators A, 139, pp. 265271 (2007).CrossRefGoogle Scholar
17.Char, J. M. and Sheu, M. S., “The Improvement of Supercritical Fluid Cleaning Mechanism by Using Spray Injector,Journal of Aeronautics, Astronautics and Aviation, Series B, 41, pp. 1724 (2009).Google Scholar
18.Pasricha, P. J., Hill, S. and Wadwa, K. S., “Endoscopic Cryospray: Experimental Results and First Clinical Use,Gastrointestinal Endoscopy, 49, pp. 627631 (1999).CrossRefGoogle Scholar
19.Kantsevoy, S. V. and Cruz-Correa, M. R., “Endoscopic Cryotherapy for the Treatment of Bleeding Mucosal Vascular Lesions of the GI Tract,Gastrointestinal Endoscopy, 57, pp. 403406 (2003).CrossRefGoogle ScholarPubMed
20.Johnston, M. H. and Schoenfeld, P., “Endoscopic Cryotherapy: A New Technique for Mucosal Ablation in the Esophagus,Gastrointestinal Endoscopy, 50, pp. 8692 (1999).CrossRefGoogle ScholarPubMed
21.Smith, D. J., Fahssi, W M., Swanlund, D. J. and Bischof, J. C., “A Parametric Study of Freezing Injury in AT-1 Rat Prostate Tumor Cells,Cryobiology, 39, pp. 1328 (1999).CrossRefGoogle ScholarPubMed
22.Onik, G. M., Cohen, J. K., Reyes, G. D., Rubinsky, B., Chang, Z. and Baust, J., “Transrectal Ultrasound Guided Percutaneous Radical Cryosurgical Ablation of the Prostate,Cancer, 72, pp. 12911299 (1993).3.0.CO;2-I>CrossRefGoogle ScholarPubMed
23.Rabb, J. M., Renaud, M. L., Brandt, A. and Witt, C. W., “Effect of Freezing and Thawing on the Microcirculation and Capillary Endothelium of the Hamster Cheek Pouch,Cryobiology, 11, pp. 508518 (1974).CrossRefGoogle ScholarPubMed
24.Rubinsky, B. and Onik, G., “Cryosurgery: Advances in the Application of Cold to Medicine,International Journal of Refrigeration, 14, pp. 190199 (1991).CrossRefGoogle Scholar
25.Raju, G. S., Ahmed, I., Xiao, S. Y., Brining, D., Bhutani, M. S. and Pasricha, P. J., “Graded Esophageal Mucosal Ablation with Cryotherapy, and the Protective Effects of Submucosal Saline,Endoscopy, 37, pp. 523526 (2005).CrossRefGoogle ScholarPubMed
26.Lin, T. C.Hong, C. Y., Shen, Y. J. and Wang, M. R., “Effects of Bypass Flow on CO2 Snow Formation for Cryogenic Application,Journal of Aeronautics, Astronautics, and Aviation, Series A, 44, pp. 193200 (2012).Google Scholar
27.Mazur, P., “Freezing of Living Cells: Mechanisms and Implications,American Journal of Physiology, 247, pp. C125C142 (1984).CrossRefGoogle ScholarPubMed
28.McGrath, J. J., Cravalho, E. G. and Huggins, C. E., “An Experimental Comparison of Intracellular Ice Formation and Freeze Thaw Survival of Hela S-3 Cells,Cryobiology, 12, pp. 540550 (1975).CrossRefGoogle ScholarPubMed
29.Jacob, G., Kurzer, M. N. and Fuller, B. J., “An Assessment of Tumor Cell Viability After in Vitro Freezing,Cryobiology, 22, pp. 417426 (1985).CrossRefGoogle ScholarPubMed
30.Blumenthal, P. D. and Mclntosh, N., Cervical Cancer Prevention Guidelines for Low-resource Settings, Jhpiego, Baltimore (2005).Google Scholar
31.Winkler, J. L., Jeronimo, J., Singleton, J., Janmohamed, A. and Santos, C., “Performance of Cryotherapy Devices Using Nitrous Oxide and Carbon Dioxide,International Journal of Gynecology and Obstetrics, 111, pp. 7377 (2010).CrossRefGoogle ScholarPubMed
32.Lin, T. C., Shen, Y. J. and Wang, M. R., “Effects of Superheat on Characteristics of Flashing Spray and Snow Particles Produced by Expanding Liquid Carbon Dioxide,Journal of Aerosol Science, 61, pp. 2735 (2013).CrossRefGoogle Scholar
33.Lin, T. C., Shen, Y. J. and Wang, M. R., “Agglomeration Processes and Mechanisms of CO2 Snow Inside a Tube,Journal of Aerosol Science and Technology, 48, pp. 228237 (2014).CrossRefGoogle Scholar