Hostname: page-component-586b7cd67f-vdxz6 Total loading time: 0 Render date: 2024-11-23T10:37:03.047Z Has data issue: false hasContentIssue false
  • English
  • Français

Control of Flow Field, Mass Transfer and Mixing Enhancement in T-Shaped Microchannels

Published online by Cambridge University Press:  13 September 2016

Y. Bazargan-Lari ,
S. Movahed  and
M. Mashhoodi
Y. Bazargan-Lari*
Affiliation:
Department of Mechanical EngineeringShiraz BranchIslamic Azad UniversityShiraz, Iran
S. Movahed
Affiliation:
Department of Mechanical EngineeringAmirkabir University of TechnologyTehran, Iran
M. Mashhoodi
Affiliation:
Young Researchers and Elites ClubScience and Research branchIslamic Azad UniversityTehran, Iran
*
*Corresponding author ([email protected])
Get access

Abstract

A T-shaped microfluidic micro-mixer was designed to mix desired concentrations of two fluid streams and to prepare their homogenous mixture solution. A hydrostatic pressure gradient was induced in one of the branches of the system (mixing channel) by applying external electric field and generating electroosmotic flow in the two other branches of the system. The flow field and transferred mass into the mixing channel can be regulated by controlling the applied voltage of the system. In order to prepare more homogenous mixture solution, some obstacles were added to the mixing channel to induce perturbation in the flow field and enhance the mixing efficiency of the system. Numerical simulations were performed to show the correctness of the proposed mixing strategy and to investigate the influences of the applied voltage on the mixing efficiency and induced pressure flow in the mixing channel. A proposed design can be used as a guideline to control and enhance mixing efficiency, and consequently functionality, of different microfluidic devices.

Keywords

MicrofluidicMixingElectrokineticsElectroosmosis
Type
Research Article
Information
Journal of Mechanics , Volume 33 , Issue 3 , June 2017 , pp. 387 - 394
Copyright
Copyright © The Society of Theoretical and Applied Mechanics 2017 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Gong, M. M., Nosrati, R., San Gabriel, M. C., Zini, A. and Sinton, D., “Direct DNA Analysis with Paper-Based Ion Concentration Polarization,” Journal of the American Chemical Society, 137, pp. 13913–13919 (2015).Google Scholar
2. Movahed, S. and Li, D., “Microfluidics cell electroporation,” Microfluidics and Nanofluidics, 10, pp. 703–734 (2011).Google Scholar
3. Nosrati, R., et al., “Rapid selection of sperm with high DNA integrity,” Lab on a Chip, 14, pp. 1142–1150 (2014).CrossRefGoogle ScholarPubMed
4. Khodaee, F., Movahed, S., Fatouraee, N. and Daneshmand, F., “Numerical Simulation of Separation of Circulating Tumor Cells from Blood Stream in Deterministic Lateral Displacement (DLD) Microfluidic Channel,” Journal of Mechanics, 32, pp. 463–471 (2016).CrossRefGoogle Scholar
5. Sohi, A. N., Nieva, P. and Khajepour, A., “A smaller footprint MEMS sensor for on-chip temperature measurement,” Reliability, Packaging, Testing, and Characterization of Moems/mems and Nanodevices XII Conference, San Francisco, United States (2013).Google Scholar
6. Sohi, A. N. and Nieva, P. M. “Frequency response of curved bilayer microcantilevers with applications to surface stress measurement,” Journal of Applied Physics, 119, 044503 (2016).Google Scholar
7. Moein-Jahromi, M., Movahed, S. and Kermani, M.J., “Numerical study of the cathode electrode in the Microfluidic Fuel Cell using agglomerate model,” Journal of Power Sources, 277, pp. 180–192 (2015).Google Scholar
8. Daw, R. and Finkelstein, J., “Lab on a chip,” Nature, 442, pp. 367–367 (2006).CrossRefGoogle Scholar
9. Li, D., Electrokinetics in Microfluidics, 1st Edition, Academic Press, Cambridge, pp. 1–643 (2004).Google Scholar
10. Kamali, R. and Movahed, S., “Dispersion control in nano-channel systems using a genetic algorithm,” Journal of Mechanics, 24, pp. 429–435 (2008).Google Scholar
11. Movahed, S. and Li, D., “Numerical studies of continuous nutrient delivery for tumour spheroid culture in a microchannel by electrokinetical-ly-induced pressure-driven flow,” Biomedical Microdevices, 12, pp. 1061–1072 (2012).CrossRefGoogle Scholar
12. Ward, K. and Fan, Z. H., “Mixing in microfluidic devices and enhancement methods,” Journal of Micromechanics and Microengineering, 25, 094001 (2015).Google Scholar
13. Lee, C.-Y., Wang, W.-T., Liu, C.-C. and Fu, L.-M., “Passive mixers in microfluidic systems: A review,” Chemical Engineering Journal, 288, pp. 146–160 (2016).CrossRefGoogle Scholar
14. Otrodi, B., Eghtesad, M., Mahzoon, M. and Movahed, S., “Control of mixing process in a novel micromixer,” Control, proceedings of 12th International Conference on Automation and Systems, Jeju Island, South Korea (2012).Google Scholar
15. Kamali, R., Shekoohi, S. A. and Binesh, A., “Effects of magnetic particles entrance arrangements on mixing efficiency of a magnetic bead micromixer,” Nano-Micro Letters, 6, pp. 30–37 (2014).CrossRefGoogle Scholar
16. Wu, Z. and Li, D., “Micromixing using induced-charge electrokinetic flow,” Electrochimica Acta, 53, pp. 5827–5835, (2008).CrossRefGoogle Scholar
17. Yu, S., Jeon, T.-J. and Kim, S. M., “Active micromixer using electrokinetic effects in the micro/nanochannel junction,” Chemical Engineering Journal, 197, pp. 289–294 (2012).CrossRefGoogle Scholar
18. Oever, J., Spannenburg, N., Offerhaus, H., Herek, J. and Mugele, F., “Acoustic micromixer fabricated by in-chip direct laser writing of microstructures,” Journal of Micro/nanolithography, MEMS, and MOEMS, 14, pp. 1–7 (2015).CrossRefGoogle Scholar
19. Chang, C.-C., Fu, L.-M. and Yang, R.-J., Active Mixer, Encyclopedia of Microfluidics and Nanofluidics, Second Edition, Springer, Berlin, pp. 40–47 (2015).CrossRefGoogle Scholar
20. Karnik, R. Microfluidic mixing, Encyclopedia of Microfluidics and Nanofluidics, Second Edition, Springer, Berlin, pp. 1969–1979 (2015).Google Scholar
21. Lee, C.-Y., Lin, C.-H. and Fu, L.-M., Passive Micromixers, Encyclopedia of Microfluidics and Nanofluidics, Second Edition, Springer, Berlin, pp. 2663–2673 (2015).CrossRefGoogle Scholar