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Making lipid membranes even tougher

Published online by Cambridge University Press:  31 January 2011

Jognandan Prashar ,
Phillip Sharp ,
Mathew Scarffe  and
Bruce Cornell
Jognandan Prashar
Affiliation:
Ambri Ltd., Chatswood, NSW 2067, Australia
Phillip Sharp
Affiliation:
Ambri Ltd., Chatswood, NSW 2067, Australia
Mathew Scarffe
Affiliation:
Ambri Ltd., Chatswood, NSW 2067, Australia
Bruce Cornell*
Affiliation:
Ambri Ltd., Chatswood, NSW 2067, Australia
*
a)Address all correspondence to this author. e-mail: [email protected]
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Abstract

Biosensors based on lipid membranes promise an inexpensive and versatile platform for application in many fields of molecular sensing. An extensive review of the applications for tethered membranes was reported in the July 2006 MRS Bulletin [A.N. Parikh and J.T. Groves, Materials science of supported lipid membranes. MRS Bull.31(8), 507 (2006)]. The commercial use to which tethered lipid membranes have been applied has been limited by their stability under long-term storage. This report describes a novel membrane construct that is stable at room temperature for months, eliminates the mobile lipid phase present in lipid bilayers, and is robust against detergents under conditions that would destroy a lipid bilayer.

Keywords

Biomimetic (assembly)SensorNanoscale
Type
Articles
Information
Journal of Materials Research , Volume 22 , Issue 8 , August 2007 , pp. 2189 - 2194
Copyright
Copyright © Materials Research Society 2007

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References

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