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Stepwise accumulation of layers of aptamer-ornamented ferritins using biomimetic layer-by-layer
Published online by Cambridge University Press: 31 January 2011
Abstract
Biomimetic layer-by-layer (BioLBL) is a layering method in which the binding and mineralization activities of a peptide aptamer are alternately used to accumulate layers of aptamer-displaying nanomaterials and thin mineral strata. We previously demonstrated this in aqua nanofabrication with BioLBL using a recombinant ferritin that displays an aptamer for titanium (minTBP-1) [K. Sano et al.: J. Am. Chem. Soc. 128, 1717 (2006); K. Sano et al.: Nano Lett.7, 3200 (2007)]. To expand the versatility of BioLBL, here we prepared a modified ferritin that was chemically ornamented with minTBP-1 and showed that BioLBL enables the formation of multiple layers of the chemically modified ferritin in a stepwise manner.
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- Information
- Journal of Materials Research , Volume 23 , Issue 12: Biomimetic and Bio-enabled Materials Science and Engineering , December 2008 , pp. 3236 - 3240
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- Copyright © Materials Research Society 2008
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