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Well-differentiated (oncocytoid) neuroendocrine carcinoma of the larynx with multiple skin metastases: a brief report

Published online by Cambridge University Press:  29 June 2007

U. Schmidt*
Affiliation:
Institute of Pathology, University of Essen, Germany.
K. A. Metz
Affiliation:
Institute of Pathology, University of Essen, Germany.
M. Schrader
Affiliation:
Institute Department of Otorhinolaryngology, University of Essen, Germany
L.-D. Leder
Affiliation:
Institute of Pathology, University of Essen, Germany.
*
Dr U. Schmidt, Institute of Pathology, University of Essen, Hufelandstr. 55, D-45122, Essen, Germany. Fax: 0201/723-5926

Abstract

A 63-year-old woman presented with a history of increasing dysphagia of about two weeks duration. Laryngoscopy revealed a nonulcerated supraglottic epitheliomatous lesion that morphologically appeared well-differentiated and distinctly oncocytoid. Although the tumour lacked any criteria for malignancy such as cellular atypia, pleomorphism or necroses, it recurred twice after primary surgery and later gave rise to multiple painful skin metastases. The diagnosis of an oncocytoid differentiated neuroendocrine carcinoma of the larynx (laryngeal carcinoid) was made. Misinterpretation of laryngeal carcinoids is common, but can be avoided if one is familiar with this rare variant of laryngeal neoplasms

Type
Pathology in Focus
Copyright
Copyright © JLO (1984) Limited 1994

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