Hostname: page-component-586b7cd67f-r5fsc Total loading time: 0 Render date: 2024-11-25T16:30:42.544Z Has data issue: false hasContentIssue false
  • English
  • Français

Well-differentiated intra-osseous osteosarcoma in the mandible of a six-year-old child

Published online by Cambridge University Press:  29 June 2007

P. L. James ,
M. B. O'regan  and
P. M. Speight
P. L. James*
Affiliation:
Consultant, Oral & Maxillo-Facial Surgery, London Hospital.
M. B. O'regan
Affiliation:
Senior Registrar, Oral & Maxillo-Facial Surgery, London Hospital.
P. M. Speight
Affiliation:
Senior Lecturer in Oral Pathology, London Hospital Medical College.
*
P. L. James, F.D.S.R.C.S., Department of Oral and Maxillo-Facial Surgery, The London Hospital, Whitechapel, London E1 1BB.
Get access Rights & Permissions [Opens in a new window]

Abstract

The case of an osteosarcoma arising in the mandible of a six-year-old child is presented. It was originally misdiagnosed as a desmoplastic fibroma, and after initial curettage continued to grow for twelve years. The differential diagnosis is presented and details of the surgical access and difficulties encountered in the surgical removal of this very large tumour are described.

The relationship between pre-existing disease and osteosarcoma of the mandible is discussed, and the difficulties experienced in distinguishing between the fibro-osseous lesions and osteosarcoma of the mandible are highlighted.

The case is presented as a well-differentiated, intra-osseous osteosarcoma with subsequent transformation into a high-grade, conventional osteosarcoma.

Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 104 , Issue 4 , April 1990 , pp. 335 - 340
Copyright
Copyright © JLO (1984) Limited 1990

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bras, H. (1982) Sarcomen van de Kaak Thesis Free University Amsterdam.Google Scholar
Caron, A. S., Hajdu, S. I., Strong, E. W. (1971) Osteogenic sarcoma of the facial and cranial bones. A review of forty-three cases. American Journal of Surgery, 122, 719.CrossRefGoogle Scholar
Clark, J. L., Unni, K. K., Dahlin, D. C., Devine, K. D. (1983) Osteosarcoma of the jaw. Cancer, 51, 2311.3.0.CO;2-Z>CrossRefGoogle ScholarPubMed
Dahlin, D. C., Coventry, M. B. (1967) Osteogenic sarcoma. A study of six hundred cases. Journal of Bone and Joint Surgery, Vol. 49-A, No. 1, 101–110.CrossRefGoogle Scholar
Dahlin, D. C. (1978) Bone tumors, 3rd Ed., Springfield, Illinois. Charles C. Thomas, 315–327 pp.Google Scholar
Garrington, G. E., Schofield, H. H., Cornyn, J., Hooker, S. D. (1967) Osteosarcoma of the jaws. Analysis of 56 cases. Cancer, 20, 377.3.0.CO;2-T>CrossRefGoogle ScholarPubMed
Huvos, A. G. (1979) Bone Tumors Diagnosis Treatment Prognosis, Saunders: Philadelphia.Google Scholar
Lucas, R. B. (1984) Pathology of tumors of the oral tissues, 4th Ed., Churchill Livingstone: Edinburgh, 197–200.Google Scholar
Porretta, C. A., Dahlin, D. C., Janes, J. M. (1957) Sarcoma in Paget's disease of bone. Journal of Bone and Joint Surgery, 39A, 1314.CrossRefGoogle Scholar
Price, C. H. G., Jeffree, G. M. (1973) Metastatic spread of osteosarcoma. British Journal of Cancer, 28, 515.CrossRefGoogle ScholarPubMed
Russ, J. E., Jesse, R. H. (1980) Management of osteosarcoma of maxilla and mandible. American Journal of Surgery, 140, 572.Google Scholar
Slootweg, P. J., Muller, H. (1985) Osteosarcoma of the jaws. Journal of Maxillofacial Surgery 13, 158–166.CrossRefGoogle Scholar
Unni, K. K., Dakin, D. C., McLeod, R. A., Pritchard, D. (1977) Intraosseous well-differentiated osteosarcoma. Cancer, 40, 1337–1347.3.0.CO;2-X>CrossRefGoogle ScholarPubMed
Yannopoulos, K., Bom, A. F., Griffiths, C. O., Crikelair, G. C. (1964) Osteosarcoma arising in fibrous dysplasia of the facial bones: Case report and review of the literature. American Journal of Surgery, 107, 556.CrossRefGoogle ScholarPubMed