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The vomeronasal organ – incidence in a Bulgarian population

Published online by Cambridge University Press:  02 February 2016

G Stoyanov*
Affiliation:
Department of Anatomy, Histology and Embryology, Medical University - Varna “Prof. Dr. Paraskev Stoyanov”, Varna, Bulgaria
K Moneva
Affiliation:
Division of Otorhinolaryngology, Department of Neurosurgery and ENT Diseases, Medical University - Varna “Prof. Dr. Paraskev Stoyanov”, Varna, Bulgaria
N Sapundzhiev
Affiliation:
Division of Otorhinolaryngology, Department of Neurosurgery and ENT Diseases, Medical University - Varna “Prof. Dr. Paraskev Stoyanov”, Varna, Bulgaria
A B Tonchev
Affiliation:
Department of Anatomy, Histology and Embryology, Medical University - Varna “Prof. Dr. Paraskev Stoyanov”, Varna, Bulgaria
*
Address for correspondence: Dr George Stoyanov, Department of Anatomy, Histology and Embryology, Medical University - Varna “Prof. Dr. Paraskev Stoyanov”, Varna, Bulgaria E-mail: [email protected]

Abstract

Background:

The vomeronasal organ is an accessory olfactory organ found in vertebrates that specialises in the chemoreception of pheromones. This study aimed to explore the existence and occurrence of the vomeronasal organ in adult humans.

Methods:

A total of 966 consecutive video recordings of out-patient nasopharyngolaryngoscopies performed at the St Marina University Hospital, Varna, Bulgaria, were retrospectively reviewed.

Results:

Data analysis showed that from the evaluable cases, the organ was evident on the left side of the nasal septum in 14.93 per cent, on the right side in 21.15 per cent and bilaterally in 2.35 per cent of cases. The vomeronasal organ was present in a total of 26.83 per cent of the investigated subjects.

Conclusion:

More research should be focused on revealing the incidence and functionality of the organ, and on its preservation in surgical manipulations that affect the nasal septum and other nearby structures.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 2016 

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Footnotes

Presented (in part) orally at the Black Sea Symposium for Young Scientists in Biomedicine, 27–30 March 2014, Varna, Bulgaria.

References

1Keverne, EB. The vomeronasal organ. Science 1999;286:716–20Google Scholar
2Døving, KB, Trotier, D. Structure and function of the vomeronasal organ. J Exp Biol 1998;201:2913–25CrossRefGoogle ScholarPubMed
3Kudjakova, TI, Sarycheva, NY, Kamensky, AA. Characteristics of exploratory behavior and the level of uneasiness of white nonpurebred rats after extirpation of the vomeronasal organ (VNO). Dokl Biol Sci 2007;414:208–11Google Scholar
4Eisthen, HL, Wysocki, CJ, Beauchamp, GK. Behavioral responses of male guinea pigs to conspecific chemical signals following neonatal vomeronasal organ removal. Physiol Behav 1987;41:445–9Google Scholar
5Knecht, M, Witt, M, Abolmaali, N, Huttenbrink, KB, Hummel, T. The human vomeronasal organ [in German]. Nervenarzt 2003;74:858–62CrossRefGoogle ScholarPubMed
6Bhatnagar, KP, Smith, TD. The human vomeronasal organ. V. An interpretation of its discovery by Ruysch, Jacobson, or Kölliker, with an English translation of Kölliker (1877). Anat Rec B New Anat 2003;270:415Google Scholar
7Bhatnagar, KP, Smith, TD. The vomeronasal organ of Jacobson in the human embryo and fetus. Otolaryngol Head Neck Surg 1979;88:119–23Google Scholar
8Smith, TD, Bhatnagar, KP. The human vomeronasal organ. Part II: prenatal development. J Anat 2000;197:421–36Google ScholarPubMed
9Lehman, MN, Newman, SW, Silverman, AJ. Luteinizing hormone-releasing hormone in the vomeronasal system and terminal nerve of the hamster. Ann N Y Acad Sci 1987;519:229–40CrossRefGoogle ScholarPubMed
10Won, J, Mair, EA, Bolger, WE, Conran, RM. The vomeronasal organ: an objective anatomic analysis of its prevalence. Ear Nose Throat J 2000;79:600–5CrossRefGoogle ScholarPubMed
11Trotier, D, Eloit, C, Wassef, M, Talmain, G, Bensimon, JL, Doving, KB et al. The vomeronasal cavity in adult humans. Chem Senses 2000;25:369–80CrossRefGoogle ScholarPubMed
12Gaafar, HA, Tantawy, AA, Melis, AA, Hennawy, DM, Shehata, HM. The vomeronasal (Jacobson's) organ in adult humans: frequency of occurrence and enzymatic study. Acta Otolaryngol 1998;118:409–12Google ScholarPubMed
13Smith, TD, Buttery, TA, Bhatnagar, KP, Burrows, AM, Mooney, MP, Siegel, MI. Anatomical position of the vomeronasal organ in postnatal humans. Ann Anat 2001;183:475–9Google Scholar
14Smith, TD, Siegel, MI, Burrows, AM, Mooney, MP, Burdi, AR, Fabrizio, PA et al. Searching for the vomeronasal organ of adult humans: preliminary findings on location, structure, and size. Microsc Res Tech 1998;41:483–91Google Scholar
15Estes, RD. The role of the vomeronasal organ in mammalian reproduction. Mammalia 1972;36:315–41CrossRefGoogle Scholar
16Kratzing, J. The structure of the vomeronasal organ in the sheep. J Anat 1971;108:247–60Google ScholarPubMed
17Sapundzhiev, N. Digital oncology patient record - heterogeneous file based approach. J IMAB 2006;16:40–3Google Scholar
18Abolmaali, ND, Kühnau, D, Knecht, M, Kohler, K, Huttenbrink, KB, Hummel, T. Imaging of the human vomeronasal duct. Chem Senses 2001;26:35–9Google Scholar
19Wessels, Q, Hoogland, P, Vorster, W. Anatomical evidence for an endocrine activity of the vomeronasal organ in humans. Clin Anat 2014;27:856–60CrossRefGoogle ScholarPubMed
20Dulac, C, Axel, R. Expression of candidate pheromone receptor genes in vomeronasal neurons. Chem Senses 1998;23:467–75Google Scholar
21Berliner, DL, Monti-Bloch, L, Jennings-White, C, Diaz-Sanchez, V. The functionality of the human vomeronasal organ (VNO): evidence for steroid receptors. J Steroid Biochem Mol Biol 1996;58:259–65Google Scholar
22Foltan, R, Sedy, J. Behavioral changes of patients after orthognathic surgery develop on the basis of the loss of vomeronasal organ: a hypothesis. Head Face Med 2009;5:5Google Scholar
23Dakrory, AI, Issa, AZ, Ali, RS. Nervi terminalis, vomeronasalis and olfactorius of Uromastyx aegyptius (squamata – lacertilia - agamidae). Life Sci J 2011;8:900–7Google Scholar
24Demski, LS, Northcutt, RG. The terminal nerve: a new chemosensory system in vertebrates? Science 1983;220:435–7CrossRefGoogle ScholarPubMed
25Demski, LS. The evolution of neuroanatomical substrates of reproductive behavior: sex steroid and LHRH-specific pathways including the terminal nerve. Amer Zool 1984;24:809–30CrossRefGoogle Scholar
26Smith, TD, Bhatnagar, KP, Shimp, KL, Kinzinger, JH, Bonar, CJ, Burrows, AM et al. Histological definition of the vomeronasal organ in humans and chimpanzees, with a comparison to other primates. Anat Rec 2002;267:166–76CrossRefGoogle ScholarPubMed
27Bhatnagar, KP, Smith, TD, Winstead, W. The human vomeronasal organ: Part IV. Incidence, topography, endoscopy, and ultrastructure of the nasopalatine recess, nasopalatine fossa, and vomeronasal organ. Am J Rhinol 2002;16:343–50Google Scholar
28Wormald, R, Lennon, P, O'Dwyer, TP. Ectopic olfactory neuroblastoma: report of four cases and a review of the literature. Eur Arch Otorhinolaryngol 2011;268:555–60Google Scholar
29Johnson, A, Josephson, R, Hawke, M. Clinical and histological evidence for the presence of the vomeronasal (Jacobson's) organ in adult humans. J Otolaryngol 1985;14:71–9Google Scholar
30Wysocki, CJ, Preti, G. Facts, fallacies, fears, and frustrations with human pheromones. Anat Rec A Discov Mol Cell Evol Biol 2004;281:1201–11CrossRefGoogle ScholarPubMed
31Meredith, M. Human vomeronasal organ function: a critical review of best and worst cases. Chem Senses 2001;26:433–45Google Scholar