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Volumetric analysis of vocal fold atrophy via magnetic resonance imaging

Published online by Cambridge University Press:  13 September 2018

S Saint-Victor ,
E Barbarite ,
C Sidani ,
R Bhatia  and
D E Rosow
S Saint-Victor
Affiliation:
Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA
E Barbarite
Affiliation:
Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA
C Sidani
Affiliation:
Department of Radiology, University of Miami Miller School of Medicine, Miami, Florida, USA
R Bhatia
Affiliation:
Department of Radiology, University of Miami Miller School of Medicine, Miami, Florida, USA
D E Rosow*
Affiliation:
Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA
*
Author for correspondence: Dr David E Rosow, 1120 NW 14th Street, 5th Floor, Miami, FL 33136, USA E-mail: [email protected] Fax: +1 305 243 2009
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Abstract

Objective

To quantitatively test the hypothesis that older patients have increased thyroarytenoid muscle atrophy by comparing thyroarytenoid muscle volumes across different age groups.

Methods

A retrospective chart review was conducted. The study included 111 patients with no history of laryngeal pathology. Two investigators reviewed magnetic resonance imaging studies of these patients and manually traced the thyroarytenoid muscles on multiple slices bilaterally. Thyroarytenoid muscle volumes were then computed using imaging analysis software. Patients were stratified into three age groups (18–50 years, 51–64 years, and 65 years or older) for comparison.

Results

Intra- and inter-rater reliabilities were excellent for all measurements (intraclass correlation co-efficient > 0.90). There was no statistically significant difference in the mean volumes of left and right thyroarytenoid muscles in all age and gender groups.

Conclusion

Given the lack of statistically significant difference in thyroarytenoid muscle volume between age groups on magnetic resonance imaging, the prevailing assumption that age-related thyroarytenoid muscle atrophy contributes to presbyphonia should be re-examined.

Keywords

DysphoniaMagnetic Resonance ImagingVocal FoldsLarynx DiseasesSenescenceGeriatrics
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 132 , Issue 9 , September 2018 , pp. 822 - 826
Copyright
Copyright © JLO (1984) Limited, 2018 

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Footnotes

Dr D E Rosow takes responsibility for the integrity of the content of the paper

Presented at the American Laryngological Association Annual Meeting, 26–28 April 2017, San Diego, California, USA.

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