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Topical antiseptic mouthwash in oncological surgery of the oral cavity and oropharynx

Published online by Cambridge University Press:  29 June 2007

Miriam I. Redleaf*
Affiliation:
Division of Otolaryngology–Head and Neck Surgery, University of Chicago Medical Centre, 5841 S. Maryland Avenue, MC 1035, Chicago, IL 60637
Carol A. Bauer
Affiliation:
Department of Otolaryngology–Head and Neck Surgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA.
*
Dr Miriam I. Redleaf, M.D., Division of Otolaryngology–Head and Neck Surgery, University of Chicago Medical Centre, 5841 S. Maryland Avenue, MC 1035, Chicago, Illinois 60637, USA.

Abstract

A multivariant analysis of the value of the use of a pre-operative topical antiseptic mouthwash to reduce the incidence of post-operative wound complications in 106 consecutive patients undergoing head and neck surgery involving the oral cavity or oropharynx was carried out at the University of Iowa, Department of Otolaryngology-Head and Neck Surgery. An oral presentation employing povidone–iodine solution was used for 43 patients. The remaining 63 patients studied received no oral presentation. Unfavourable wound outcome was not associated with age, sex, presence and condition of teeth, or serious pre-existing medical illnesses. A significant correlation was found between post-operative wound breakdown and type of closure, stage of disease, and previous operation or radiotherapy. The use of an oral preparation correlated significantly with favourable wound outcome independent of all other variables (p<0.01).

Our data support the use of a topical antiseptic mouthwash to reduce the incidence of post-operative wound complications in surgery of the oral cavity and oropharynx.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 1994

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Footnotes

This manuscript was presented to the American Society for Head and Neck Surgery, Spring Meeting (April 21,1993) in Los Angeles, CA, USA.

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