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Sudden hearing loss in chronic myelogenous leukaemia implicating the hyperviscosity syndrome

Published online by Cambridge University Press:  08 March 2006

Sung Won Chae ,
Jae Hoon Cho ,
Jang Hyuck Lee ,
Hee Joon Kang  and
Soon Jae Hwang
Sung Won Chae
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Korea University, Seoul, Korea.
Jae Hoon Cho
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Korea University, Seoul, Korea.
Jang Hyuck Lee
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Korea University, Seoul, Korea.
Hee Joon Kang
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Korea University, Seoul, Korea.
Soon Jae Hwang
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Korea University, Seoul, Korea.
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Abstract

Sudden sensorineural hearing loss that presents as the initial sign of haematological disease is very rare. Chronic myelogenous leukaemia has been implicated as a causative factor of sudden sensorineural hearing loss.

A 49-year-old male presented with unilateral sudden sensorineural hearing loss. The patient was found to have chronic myelogenous leukaemia during a work-up for his hearing loss. We present a case of a chronic myelogenous leukaemia patient whose first manifestation was sudden sensorineural hearing loss. We presume that cochlear vessel occlusion as a result of elevated blood viscosity was responsible for this patient’s hearing loss. Early onset of sudden deafness in a chronic myelogenous leukaemia patient may be due to the hyperviscosity syndrome and it may be possible to reverse hearing loss through early leukapheresis.

Keywords

Hearing LossSensorineuralBlood ViscosityLeukaemiaMyeloidChronic
Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 116 , Issue 4 , April 2002 , pp. 291 - 293
Copyright
© Royal Society of Medicine Press Limited 2002

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