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Submandibular gland invasion and feasibility of gland-sparing neck dissection in oral cavity carcinoma

Published online by Cambridge University Press:  03 May 2018

A Cakir Cetin ,
E Dogan ,
H Ozay ,
O Kumus ,
T K Erdag ,
N Karabay ,
S Sarioglu  and
A O Ikiz
A Cakir Cetin*
Affiliation:
Department of ENT, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey
E Dogan
Affiliation:
Department of ENT, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey
H Ozay
Affiliation:
Department of ENT, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey
O Kumus
Affiliation:
Department of ENT, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey
T K Erdag
Affiliation:
Department of ENT, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey
N Karabay
Affiliation:
Department of Radiology, Dokuz Eylul University, Izmir, Turkey
S Sarioglu
Affiliation:
Department of Pathology, Dokuz Eylul University, Izmir, Turkey
A O Ikiz
Affiliation:
Department of ENT, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey
*
Address for correspondence: Dr Asli Cakir Cetin, Dokuz Eylul Universitesi Tip Fakultesi Hastanesi, Kulak Burun Bogaz Anabilim Dali, Balcova, Izmir 35340, Turkiye Fax: +90 232 412 32 96 E-mail: [email protected]
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Abstract

Objective:

This study investigated the incidence and routes of submandibular gland involvement in oral cavity carcinoma to determine the feasibility of submandibular gland sparing neck dissection.

Methods:

The records of 155 patients diagnosed with oral cavity squamous cell carcinoma, with a total of 183 neck specimens, including those involving level I, were reviewed retrospectively.

Results:

Submandibular gland involvement, via direct invasion from the anatomical proximity of T4a tumours, was evident in two patients. The floor of mouth location, either primarily or as an extension of the primary tumour, was the only risk factor for submandibular gland involvement in oral cavity carcinoma (p = 0.042). Tumour location, clinical and pathological tumour (T) and nodal (N) stages, and radiological suspicion of mandible invasion, were not found to be statistically relevant (p > 0.05).

Conclusion:

The results suggest the feasibility of preserving the submandibular gland in early stage oral cavity carcinoma unless the tumour is located in, or extends to, the floor of mouth.

Keywords

Oral NeoplasmsSubmandibular GlandOrgan PreservationNeck DissectionSquamous Cell Cancer
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 132 , Issue 5 , May 2018 , pp. 446 - 451
Copyright
Copyright © JLO (1984) Limited 2018 

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