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Soft tissue reaction to ceramic ossicular replacement prosthesis

Published online by Cambridge University Press:  29 June 2007

Etsuo Yamamoto  and
Michitaka Iwanaga
Etsuo Yamamoto*
Affiliation:
Kyoto, Japan
Michitaka Iwanaga
Affiliation:
Kyoto, Japan
*
Department of Otolaryngology, Faculty of Medicine, Kyoto University, Sakyo-ku, Kyoto, 606Japan.
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Abstract

Soft-tissue reaction to ceramic ossicular replacement prostheses (CORP) has been evaluated histologically in rabbits and humans. One week after implantation, severe inflammatory and foreign body reaction was observed in the fibrous connective tissue surrounding the prosthesis. Though some inflammatory response was seen after one month, after three months the CORP was surrounded by a layer of fibrous connective tissue without any foreigh body giant cell, histiocyte or inflammatory cell infiltration. Our satisfactory clinical results in humans without placing a cartilage between the CORP and the fascia graft may be due to the excellent softtissue compatibility of CORP, as demonstrated in this study.

Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 101 , Issue 9 , September 1987 , pp. 897 - 904
Copyright
Copyright © JLO (1984) Limited 1987

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