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Sinus computerized tomography in primary hypogammaglobulinaemia

Published online by Cambridge University Press:  29 June 2007

D. G. Snow*
Affiliation:
Department of Otolaryngology, Queen Elizabeth Hospital, Edgbaston, Birmingham B 15
T. T. Hansel
Affiliation:
Regional Department of Immunology, East Birmingham Hospital, Bordesley Green East, Birmingham B9 5ST
P. E. Williams
Affiliation:
Regional Department of Immunology, East Birmingham Hospital, Bordesley Green East, Birmingham B9 5ST
A. B. Drake-Lee
Affiliation:
Department of Otolaryngology, Queen Elizabeth Hospital, Edgbaston, Birmingham B 15
R. A. Thompson
Affiliation:
Regional Department of Immunology, East Birmingham Hospital, Bordesley Green East, Birmingham B9 5ST
*
Mr David Snow, F.R.C.S., ENT Department, Dudley Road Hospital, Dudley Road, Birmingham

Abstract

Thirteen patients suffering from primary hypogammaglobulinaemia receiving intravenous immunoglobulin replacement therapy underwent computerized tomography of the paranasal sinuses. The CT scans were evaluated and related to clinical data from the patients, who were selected for study on the basis of having symptoms of rhinosinusitis. The scans varied from normal to demonstrating widespread sinus abnormality. Th.ere was no relationship between the scan findings and duration of ENT symptoms, range of current symptoms, or the interval between the onset of ENT symptoms and the start of intravenous immunoglobulin replacement therapy. It is nevertheless possible that prompt institution of replacement therapy, after correct diagnosis early in the course of the disease, may prevent the development of sinus disease refractory to such treatment.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 1993

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