Hostname: page-component-586b7cd67f-vdxz6 Total loading time: 0 Render date: 2024-11-26T22:25:22.706Z Has data issue: false hasContentIssue false
  • English
  • Français

Second primary tumour following retinoblastoma

Published online by Cambridge University Press:  29 June 2007

D. C. Berridge ,
A. Hitchcock ,
P. J. Bradley  and
L. Kapila
D. C. Berridge*
Affiliation:
Department of Paediatric Surgery, University Hospital, Queen's Medical Centre, Nottingham NG7 2UH
A. Hitchcock
Affiliation:
Histopathology, University Hospital, Queen's Medical Centre, Nottingham NG7 2UH
P. J. Bradley
Affiliation:
Otolarngology/Head and Neck Oncology, University Hospital, Queen's Medical Centre, Nottingham NG7 2UH
L. Kapila
Affiliation:
Department of Paediatric Surgery, University Hospital, Queen's Medical Centre, Nottingham NG7 2UH
*
Mr. D. C. Berridge, Department of Paediatric Surgery, E Floor, East Block, University Hospital, Queen's Medical Centre, Nottingham. NG7 2UH
Get access Rights & Permissions [Opens in a new window]

Abstract

Reported is a child who at the age of 18 months had presented with a left retinoblastoma. The lesion had involved the optic nerve (Stage IV), and was successfully treated by enucleation and radiotherapy. The radiation field did not include the mandible or the submandibular triangle. He was followed up until he left the area aged 11 years. He represented aged 12 years with a progressive swelling of the left submandibular gland. Histology of the surgically excised submandibular gland revealed a mucoepidermoid carcinoma of the submandibular gland. This case highlights the need for continual surveillance in survivors of retinoblastoma, as second primary tumours occur both within and outside of previous radiation fields. The clinical association between retinoblastoma and mucoepidermoid carcinoma of the submandibular gland has not been previously reported.

Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 103 , Issue 7 , July 1989 , pp. 690 - 691
Copyright
Copyright © JLO (1984) Limited 1989

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Abramson, D. H., Ellsworth, R. M., Kitchin, D. and Tung, G. (1984) Second non-ocular tumours in retinoblastoma survivors Ophthalmology, 91: 1351–1355.CrossRefGoogle Scholar
Bedford, M. A., Bedotto, C. and MacFaul, P. A. (1971) Retinoblastoma. A study of 139 cases. British Journal of Ophthalmology. 55: 19–27.CrossRefGoogle ScholarPubMed
Evans, H. L. (1984) Mucoepidermoid carcinoma of salivary glands: A study of 69 cases with special attention to histologic grading. American Journal of Pathology. 81: 696–701.Google ScholarPubMed
Lennox, G. I., Draper, G. J. and Saunders, B. M. (1975) Nonocular tumours in retinoblastoma survivors. British Medical Journal. 3: 731–734.CrossRefGoogle Scholar
Lueder, G. T., Judisch, J. and O'Gorman, W. (1986) Second nonocular tumours in survivors of heritable retinoblastoma. Archives of Ophthalmology, 104: 372–373.CrossRefGoogle ScholarPubMed
Thordvalsson, S. E., Beahrs, O. H., Woolner, L. B. and Simons, J. N. (1970) Mucoepidermoid tumours of the major salivary glands. American Journal of Surgery. 120: 432–438.CrossRefGoogle Scholar