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Sebaceoma of the auricle

Published online by Cambridge University Press:  08 June 2012

J P Jacobson*
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, NYU Langone Medical Center, New York, USA
A Weisstuch
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, NYU Langone Medical Center, New York, USA
C Hajdu
Affiliation:
Department of Pathology, NYU Langone Medical Center, New York, USA
D Myssiorek
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, NYU Langone Medical Center, New York, USA
*
Address for correspondence: Dr Joel Jacobson, Department of Otolaryngology-Head and Neck Surgery, UC Davis Medical Center, 2521 Stockton Blvd, Suite 5200, Sacramento, CA 95817, USA E-mail: [email protected]

Abstract

Objective:

To report a case of sebaceoma of the auricle, and to discuss the differential diagnosis, histopathological features, surgical management and genetic associations of this entity.

Methods:

Case report and review of the medical literature.

Results:

A 79-year-old man presented with a slowly growing lesion of his auricle. Excision of the mass and histopathological review revealed a benign, basaloid, adnexal neoplasm consistent with sebaceoma. Due to its association with Muir–Torre syndrome and increased risk of visceral malignancy, the patient was followed closely for signs of malignancy. At 36 months post-excision, there were no signs of recurrence; thereafter, the patient continued to receive routine cancer surveillance follow up.

Conclusion:

Sebaceoma is a rarely encountered, benign, adnexal neoplasm which can occur in the head and neck. The treatment is surgical excision, and recurrence is rare. Sebaceoma can occur as part of Muir–Torre syndrome, and in these patients there is an increased risk of other sebaceous lesions and visceral malignancy; thus, genetic testing and surveillance should be strongly considered.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 2012

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References

1 Misago, N, Mihara, I, Ansai, S, Narisawa, Y. Sebaceoma and related neoplasms with sebaceous differentiation: a clinicopathologic study of 30 cases. Am J Dermatopathol 2002;24:294304 CrossRefGoogle ScholarPubMed
2 Fan, YS, Carr, RA, Sanders, DSA, Smith, AP, Lazar, AJF, Calonje, E. Characteristic Ber-EP4 and EMA expression in sebaceoma is immunohistochemically distinct from basal cell carcinoma. Histopathology 2007;51:80–6CrossRefGoogle ScholarPubMed
3 Eisen, DB, Michael, DJ. Sebaceous lesions and their associated syndromes: Part I. J Am Acad Dermatol 2009;61:549–60CrossRefGoogle ScholarPubMed
4 Ponti, G, Ponz de Leon, M. Muir-Torre syndrome. Lancet Oncology 2005;6:980–7CrossRefGoogle ScholarPubMed
5 Willey, A, Swanson, NA, Lee, KK. Cumming's Otolaryngology-Head and Neck Surgery, 5th edn. Philadelphia: Mosby Elsevier, 2010 Google Scholar
6 Alsaad, KO, Obaidat, NA, Ghazarian, D. Skin adnexal neoplasms – part 1. An approach to tumours of the pilosebaceous unit. J Clinical Pathol 2007;60:129–44CrossRefGoogle ScholarPubMed
7 Demellawy, DE, Nicholas, E, Salama, S, Alowami, S. Sebaceoma of the external ear canal: an unusual location. Case report and review of the literature. J Cutan Pathol 2008;3:963–6CrossRefGoogle Scholar
8 Troy, JL, Ackerman, AB. Sebaceoma. A distinctive benign neoplasm of adnexal epithelium differentiating toward sebaceous cells. Am J Dermatopathol 1984;6:713 CrossRefGoogle ScholarPubMed
9 Lachiewicz, A, Wilkinson, T, Groben, P, Ollila, DW, Thomas, N. Muir Torre syndrome. Am J Clin Dermatol 2007;8:315–9CrossRefGoogle ScholarPubMed
10 Abbas, O, Mahalingam, M. Cutaneous sebaceous neoplasms as markers of Muir-Torre syndrome: a diagnostic algorithm. J Cutan Pathol 2009;36:613–9CrossRefGoogle ScholarPubMed
11 Demirci, H, Nelson, CC, Shields, CL, Eagle, RC Jr, Shields, JA. Eyelid sebaceous carcinoma associated with Muir-Torre syndrome in two cases. Ophthal Plast Reconstr Surg 2007;23:77–9CrossRefGoogle ScholarPubMed