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Scytalidium dimidiatum associated invasive fungal sinusitis in an immunocompetent patient

Published online by Cambridge University Press:  02 October 2014

A Hariri*
Affiliation:
Department of ENT, Charing Cross Hospital, Imperial College Healthcare NHS Trust, UK
N Choudhury
Affiliation:
Department of ENT, Charing Cross Hospital, Imperial College Healthcare NHS Trust, UK
H A Saleh
Affiliation:
Department of ENT, Charing Cross Hospital, Imperial College Healthcare NHS Trust, UK
*
Address for correspondence: Dr Ahmad Hariri, Department of ENT, Charing Cross Hospital, Fulham Palace Road, London W6 9NT, UK Fax: 0203 311 5088 E-mail: [email protected]

Abstract

Background:

Scytalidium dimidiatum is a soil and plant pathogen that frequently affects fruit trees, but can also cause human infection. There are only two reported cases of invasive fungal sinusitis involving this rare micro-organism.

Objective:

This paper reports the first case of invasive fungal sinusitis caused by Scytalidium dimidiatum occurring in a young immunocompetent patient from a non-endemic region, and discusses potential sources of exposure and relevance of local factors.

Method:

Case report.

Results:

The patient was treated successfully with a combination of functional endoscopic sinus surgery, and antifungal and corticosteroid treatment.

Conclusion:

This paper describes the first reported case of invasive fungal sinusitis secondary to Scytalidium dimidiatum in a young immunocompetent patient from a non-endemic region. Importance is placed on following a systematic process of investigation and management, and adhering to well-defined basic surgical principles.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 2014 

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References

1Frankel, DH, Rippon, JW. Hendersonula toruloidea infection in man. Index cases in the non-endemic North American host, and a review of the literature. Mycopathologia 1989;105:175–86Google Scholar
2Elinav, H, Izhar, U, Benenson, S, Admon, D, Hidalgo-Grass, C, Polacheck, I et al. Invasive Scytalidium dimidiatum infection in an immunocompetent adult. J Clin Microbiol 2009;47:1259–63Google Scholar
3Turner, JH, Soudry, E, Nayak, JV, Hwang, PH. Survival outcomes in acute invasive fungal sinusitis: a systematic review and quantitative synthesis of published evidence. Laryngoscope 2013;123:1112–18CrossRefGoogle ScholarPubMed
4Chen, CY, Sheng, WH, Cheng, A, Chen, YC, Tsay, W, Tang, JL et al. Invasive fungal sinusitis in patients with hematological malignancy: 15 years experience in a single university hospital in Taiwan. BMC Infect Dis 2011;11:250CrossRefGoogle Scholar
5Almyroudis, N, Sutton, D, Linden, P, Rinaldi, M, Fung, J, Kusne, S. Zygomycosis in solid organ transplant recipients in a tertiary transplant center and review of the literature. Am J Transplant 2006;6:2365–74CrossRefGoogle Scholar
6Sydow, H, Sydow, P, Butler, E. Fungi Indiae orientalis pars V. Annales Mycologici 1916;14:177220Google Scholar
7Khan, Z, Ahmad, S, Joseph, L, Chandy, R. Cutaneous phaeohyphomycosis due to Neoscytalidium dimidiatum: first case report from Kuwait. Journal of Medical Mycology 2009;19:138–42Google Scholar
8Morris-Jones, R, Youngchim, S, Hextall, JM, Gomez, BL, Morris-Jones, SD, Hay, RJ et al. Scytalidium dimidiatum causing recalcitrant subcutaneous lesions produces melanin. J Clin Microbiol 2004;42:3789–94CrossRefGoogle ScholarPubMed
9al-Rajhi, AA, Awad, AH, al-Hedaithy, S, Forster, RK, Caldwell, KC. Scytalidium dimidiatum fungal endophthalmitis. Br J Ophthalmol 1993;77:388–90CrossRefGoogle ScholarPubMed
10Benne, C, Neeleman, C, Bruin, M, De Hoog, G, Fleer, A. Disseminating infection with Scytalidium dimidiatum in a granulocytopenic child. Eur J Clin Microbiol Infect Dis 1993;12:118–21CrossRefGoogle Scholar
11Dunn, JJ, Wolfe, MJ, Trachtenberg, J, Kriesel, JD, Orlandi, RR, Carroll, KC. Invasive fungal sinusitis caused by Scytalidium dimidiatum in a lung transplant recipient. J Clin Microbiol 2003;41:5817–19Google Scholar
12Geramishoar, M, Zomorodian, K, Zaini, F, Saadat, F, Tarazooie, B, Norouzi, M et al. First case of cerebral phaeohyphomycosis caused by Nattrassia mangiferae in Iran. Jpn J Infect Dis 2004;57:285–6Google Scholar
13Gumbo, T, Mkanganwi, N, Robertson, VJ, Masvaire, P. Case report. Nattrassia mangiferae endophthalmitis. Mycoses 2002;45:118–19CrossRefGoogle ScholarPubMed
14Mani, RS, Chickabasaviah, YT, Nagarathna, S, Chandramuki, A, Shivprakash, MR, Vijayan, J et al. Cerebral phaeohyphomycosis caused by Scytalidium dimidiatum: a case report from India. Med Mycol 2008;46:705–11CrossRefGoogle ScholarPubMed
15Sadeghi Tari, A, Mardani, M, Rahnavardi, M, Asadi Amoli, F, Abedinifar, Z. Post-traumatic fatal Nattrassia mangiferae orbital infection. Int Ophthalmol 2005;26:247–50CrossRefGoogle ScholarPubMed
16Tan, DHS, Sigler, L, Gibas, CFC, Fong, IW. Disseminated fungal infection in a renal transplant recipient involving Macrophomina phaseolina and Scytalidium dimidiatum: case report and review of taxonomic changes among medically important members of the Botryosphaeriaceae. Med Mycol 2008;46:285–92Google Scholar
17Willinger, B, Kopetzky, G, Harm, F, Apfalter, P, Makristathis, A, Berer, A et al. Disseminated infection with Nattrassia mangiferae in an immunosuppressed patient. J Clin Microbiol 2004;42:478–80CrossRefGoogle Scholar
18Ikram, A, Hussain, W, Satti, ML, Wiqar, MA. Invasive infection in a young immunocompetent soldier caused by Scytalidium dimidiatum. J Coll Physicians Surg Pak 2009;19:64–6Google Scholar