Hostname: page-component-78c5997874-dh8gc Total loading time: 0 Render date: 2024-11-16T19:25:16.483Z Has data issue: false hasContentIssue false
  • English
  • Français

Role of cervical vestibular evoked myogenic potential response in identifying vestibular dysfunction

Published online by Cambridge University Press:  08 August 2013

S Isaradisaikul ,
N Navacharoen ,
C Hanprasertpong  and
J Kangsanarak
S Isaradisaikul*
Affiliation:
Department of Otolaryngology, Faculty of Medicine, Chiang Mai University, Thailand
N Navacharoen
Affiliation:
Department of Otolaryngology, Faculty of Medicine, Chiang Mai University, Thailand
C Hanprasertpong
Affiliation:
Department of Otolaryngology, Faculty of Medicine, Chiang Mai University, Thailand
J Kangsanarak
Affiliation:
Department of Otolaryngology, Faculty of Medicine, Chiang Mai University, Thailand
*
Address for correspondence: Dr Suwicha Isaradisaikul, Department of Otolaryngology, Faculty of Medicine, Chiang Mai University, 110 Intawaroros Rd, Sriphum, Mueang, Chiang Mai 50200, Thailand Fax: +66 53 945564 E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Objectives:

To analyse cervical vestibular evoked myogenic potential response parameters in normal volunteers and vertiginous patients.

Subjects and methods:

A prospective study of 50 normal subjects and 50 patients with vertigo was conducted at Chiang Mai University Hospital, Thailand. Cervical vestibular evoked myogenic potential responses were measured using air-conducted, 500-Hz, tone-burst stimuli with subjects in a sitting position with their head turned toward the contralateral shoulder.

Results:

The mean ± standard deviation age and male:female ratio in the normal (44.0 ± 9.3 years; 12:38) and vertigo groups (44.7 ± 9.8 years; 17:33) were not significantly different. The prevalence of absent responses in the normal (14 per cent) and vertigo ears (46 per cent) differed significantly (p < 0.0001). Other cervical vestibular evoked myogenic potential parameters (i.e. response threshold, P1 and N1 latency, P1–N1 interlatency and interamplitude, inter-ear difference in P1 threshold, and asymmetry ratio) showed no inter-group differences.

Conclusion:

The absence of a cervical vestibular evoked myogenic potential response is useful in the identification of vestibular dysfunction. However, patients should undergo a comprehensive battery of other vestibular tests to supplement their cervical vestibular evoked myogenic potential response findings.

Keywords

Vestibular Evoked Myogenic PotentialsVestibular Function TestsVertigoDiagnosis
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 9 , September 2013 , pp. 848 - 853
Copyright
Copyright © JLO (1984) Limited 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Presented at the American Academy of Otolaryngology – Head and Neck Surgery Foundation 115th Annual Meeting and Oto Expo, 11–14 September 2011, San Francisco, California, USA

References

1Wuyts, FL, Furman, J, Vanspauwen, R, Van De Heyning, P. Vestibular function testing. Curr Opin Neurol 2007;20:19–24CrossRefGoogle ScholarPubMed
2Zhou, G, Cox, LC. Vestibular evoked myogenic potentials: history and overview. Am J Audiol 2004;13:135–43CrossRefGoogle ScholarPubMed
3Bickford, RG, Jacobson, JL, Cody, DT. Nature of average evoked potentials to sound and other stimuli in man. Ann N Y Acad Sci 1964;112:204–23CrossRefGoogle ScholarPubMed
4Townsend, GL, Cody, DT. The averaged inion response evoked by acoustic stimulation: its relation to the saccule. Ann Otol Rhinol Laryngol 1971;80:121–31CrossRefGoogle Scholar
5Colebatch, JG, Halmagyi, GM, Skuse, NF. Myogenic potentials generated by a click-evoked vestibulocollic reflex. J Neurol Neurosurg Psychiatry 1994;57:190–7CrossRefGoogle ScholarPubMed
6Welgampola, MS, Colebatch, JG. Characteristics and clinical applications of vestibular-evoked myogenic potentials. Neurology 2005;64:1682–8CrossRefGoogle ScholarPubMed
7Eleftheriadou, A, Koudounarakis, E. Vestibular-evoked myogenic potentials eliciting: an overview. Eur Arch Otorhinolaryngol 2011;268:331–9CrossRefGoogle ScholarPubMed
8Park, HJ, Lee, IS, Shin, JE, Lee, YJ, Park, MS. Frequency-tuning characteristics of cervical and ocular vestibular evoked myogenic potentials induced by air-conducted tone bursts. Clin Neurophysiol 2010;121:85–9CrossRefGoogle ScholarPubMed
9Ochi, K, Ohashi, T, Nishino, H. Variance of vestibular-evoked myogenic potentials. Laryngoscope 2001;111:522–7CrossRefGoogle ScholarPubMed
10Young, YH. Vestibular evoked myogenic potentials: optimal stimulation and clinical application. J Biomed Sci 2006;13:745–51CrossRefGoogle ScholarPubMed
11Chiarovano, E, Zamith, F, Vidal, PP, de Waele, C. Ocular and cervical VEMPs: a study of 74 patients suffering from peripheral vestibular disorders. Clin Neurophysiol 2011;122:1650–9CrossRefGoogle ScholarPubMed
12De Oliveira Barreto, AC, Colafamina, JF, De Lemos Menezes, P. Saccular sensitivity function measured by vestibular evoked myogenic potential. Acta Otolaryngol 2011;131:618–23CrossRefGoogle ScholarPubMed
13Janky, KL, Shepard, N. Vestibular evoked myogenic potential (VEMP) testing: normative threshold response curves and effects of age. J Am Acad Audiol 2009;20:514–22Google ScholarPubMed
14Maes, L, Vinck, BM, De Vel, E, D'haenens, W, Bockstael, A, Keppler, H et al. The vestibular evoked myogenic potential: a test-retest reliability study. Clin Neurophysiol 2009;120:594–600CrossRefGoogle ScholarPubMed
15Isaradisaikul, S, Strong, DA, Moushey, JM, Gabbard, SA, Ackley, SR, Jenkins, HA. Reliability of vestibular evoked myogenic potentials in healthy subjects. Otol Neurotol 2008;29:542–44CrossRefGoogle ScholarPubMed
16Wu, HJ, Shiao, AS, Yang, YL, Lee, GS. Comparison of short tone burst-evoked and click-evoked vestibular myogenic potentials in healthy individuals. J Chin Med Assoc 2007;70:159–63CrossRefGoogle ScholarPubMed
17Picciotti, PM, Fiorita, A, Di Nardo, W, Calo, L, Scarano, E, Paludetti, G. Vestibular evoked myogenic potentials in children. Int J Pediatr Otorhinolaryngol 2007;71:29–33CrossRefGoogle ScholarPubMed
18Kelsch, TA, Schaefer, LA, Esquivel, CR. Vestibular evoked myogenic potentials in young children: test parameters and normative data. Laryngoscope 2006;116:895–900CrossRefGoogle ScholarPubMed
19Wang, CT, Young, YH. Comparison of the head elevation versus rotation methods in eliciting vestibular evoked myogenic potentials. Ear Hear 2006;27:376–81CrossRefGoogle ScholarPubMed
20Basta, D, Todt, I, Ernst, A. Normative data for P1/N1-latencies of vestibular evoked myogenic potentials induced by air- or bone-conducted tone bursts. Clin Neurophysiol 2005;116:2216–19CrossRefGoogle ScholarPubMed
21Su, HC, Huang, TW, Young, YH, Cheng, PW. Aging effect on vestibular evoked myogenic potential. Otol Neurotol 2004;25:977–80CrossRefGoogle ScholarPubMed
22Cheng, PW, Huang, TW, Young, YH. The influence of clicks versus short tone bursts on the vestibular evoked myogenic potentials. Ear Hear 2003;24:195–7CrossRefGoogle ScholarPubMed
23Wang, SJ, Young, YH. Vestibular evoked myogenic potentials using simultaneous binaural acoustic stimulation. Hear Res 2003;185:43–8CrossRefGoogle ScholarPubMed
24Patko, T, Vidal, PP, Vibert, N, Tran Ba Huy, P, De Waele, C. Vestibular evoked myogenic potentials in patients suffering from a unilateral acoustic neuroma: a study of 170 patients. Clin Neurophysiol 2003;114:1344–50CrossRefGoogle ScholarPubMed
25Wu, CH, Young, YH, Murofushi, T. Tone burst-evoked myogenic potentials in human neck flexor and extensor. Acta Otolaryngol 1999;119:741–4Google ScholarPubMed
26Akin, FW, Murnane, OD, Proffitt, TM. The effects of click and tone-burst stimulus parameters on the vestibular evoked myogenic potential (VEMP). J Am Acad Audiol 2003;14:500–9Google ScholarPubMed
27Rauch, SD, Zhou, G, Kujawa, SG, Guinan, JJ, Herrmann, BS. Vestibular evoked myogenic potentials show altered tuning in patients with Meniere's disease. Otol Neurotol 2004;25:333–8CrossRefGoogle ScholarPubMed
28Akin, FW, Murnane, OD, Panus, PC, Caruthers, SK, Wilkinson, AE, Proffitt, TM. The influence of voluntary tonic EMG level on the vestibular-evoked myogenic potential. J Rehabil Res Dev 2004;41:473–80CrossRefGoogle ScholarPubMed
29Brantberg, K, Fransson, PA. Symmetry measures of vestibular evoked myogenic potentials using objective detection criteria. Scand Audiol 2001;30:189–96CrossRefGoogle ScholarPubMed
30Welgampola, MS, Colebatch, JG. Vestibulocollic reflexes: normal values and the effect of age. Clin Neurophysiol 2001;112:1971–9CrossRefGoogle ScholarPubMed
31Nguyen, KD, Welgampola, MS, Carey, JP. Test-retest reliability and age-related characteristics of the ocular and cervical vestibular evoked myogenic potential tests. Otol Neurotol 2010;31:793–802CrossRefGoogle ScholarPubMed
32De Waele, C, Tran Ba Huy, P, Diard, JP, Freyss, G, Vidal, PP. Saccular dysfunction in Meniere's disease. Am J Otol 1999;20:223–32Google ScholarPubMed
33Iwasaki, S, Takai, Y, Ozeki, H, Ito, K, Karino, S, Murofushi, T. Extent of lesions in idiopathic sudden hearing loss with vertigo: study using click and galvanic vestibular evoked myogenic potentials. Arch Otolaryngol Head Neck Surg 2005;131:857–62CrossRefGoogle ScholarPubMed
34Murofushi, T, Shimizu, K, Takegoshi, H, Cheng, PW. Diagnostic value of prolonged latencies in the vestibular evoked myogenic potential. Arch Otolaryngol Head Neck Surg 2001;127:1069–72CrossRefGoogle ScholarPubMed
35Ushio, M, Matsuzaki, M, Takegoshi, H, Murofushi, T. Click- and short tone burst-evoked myogenic potentials in cerebellopontine angle tumors. Acta Otolaryngol Suppl 2001;545:133–5Google ScholarPubMed
36Versino, M, Colnaghi, S, Callieco, R, Cosi, V. Vestibular evoked myogenic potentials: Test-retest reliability. Funct Neurol 2001;16:299–309Google ScholarPubMed
37Ushio, M, Iwasaki, S, Murofushi, T, Sugasawa, K, Chihara, Y, Fujimoto, C et al. The diagnostic value of vestibular-evoked myogenic potential in patients with vestibular schwannoma. Clin Neurophysiol 2009;120:1149–53CrossRefGoogle ScholarPubMed
38Akkuzu, G, Akkuzu, B, Ozluoglu, LN. Vestibular evoked myogenic potentials in benign paroxysmal positional vertigo and Meniere's disease. Eur Arch Otorhinolaryngol 2006;263:510–17CrossRefGoogle ScholarPubMed
39Chen, CN, Young, YH. Differentiating the cause of acute sensorineural hearing loss between Meniere's disease and sudden deafness. Acta Otolaryngol 2006;126:25–31CrossRefGoogle ScholarPubMed
40Young, YH, Huang, TW, Cheng, PW. Assessing the stage of Meniere's disease using vestibular evoked myogenic potentials. Arch Otolaryngol Head Neck Surg 2003;129:815–18CrossRefGoogle ScholarPubMed
41Wu, CC, Young, YH. Vestibular evoked myogenic potentials are intact after sudden deafness. Ear Hear 2002;23:235–8CrossRefGoogle ScholarPubMed
42Govender, S, Rosengren, SM, Colebatch, JG. Vestibular neuritis has selective effects on air- and bone-conducted cervical and ocular vestibular evoked myogenic potentials. Clin Neurophysiol 2011;122:1246–55CrossRefGoogle ScholarPubMed
43Roditi, RE, Eppsteiner, RW, Sauter, TB, Lee, DJ. Cervical vestibular evoked myogenic potentials (cVEMPs) in patients with superior canal dehiscence syndrome (SCDS). Otolaryngol Head Neck Surg 2009;141:24–8CrossRefGoogle ScholarPubMed
44Chang, CH, Young, YH. Caloric and vestibular evoked myogenic potential tests in evaluating children with benign paroxysmal vertigo. Int J Pediatr Otorhinolaryngol 2007;71:495–9CrossRefGoogle ScholarPubMed
45Faralli, M, Molini, E, Ricci, G, Scardazza, R, Trabalzini, F, Altissimi, G et al. Study of vestibular evoked myogenic potentials in unilateral vestibulopathy: otolithic versus canal function testing. Otol Neurotol 2006;27:1115–19CrossRefGoogle ScholarPubMed
46Liao, LJ, Young, YH. Vestibular evoked myogenic potentials in basilar artery migraine. Laryngoscope 2004;114:1305–9CrossRefGoogle ScholarPubMed
47Lu, YC, Young, YH. Vertigo from herpes zoster oticus: superior or inferior vestibular nerve origin? Laryngoscope 2003;113:307–11CrossRefGoogle ScholarPubMed