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Results for audiology and distortion product and transient evoked otoacoustic emissions in patients with systemic lupus erythematosus

Published online by Cambridge University Press:  26 October 2009

H Karabulut ,
M Dagli ,
A Ates  and
Y Karaaslan
H Karabulut
Affiliation:
Otolaryngology Department, Ankara Keciören Research and Training Hospital, Turkey
M Dagli*
Affiliation:
Department of Otolaryngology, Ankara Numune Research and Training Hospital, Turkey
A Ates
Affiliation:
Department of Rheumatology, Ankara Numune Research and Training Hospital, Turkey
Y Karaaslan
Affiliation:
Department of Rheumatology, Ankara Numune Research and Training Hospital, Turkey
*
Address for correspondence: Dr Muharrem Dagli, Cemal Gursel Caddesi no 48/1, Cebeci 06600, Ankara, Turkey. Fax: 903124358832 E-mail: [email protected]
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Abstract

The aim of the current study was to investigate hearing loss and cochlear function in patients with systemic lupus erythematosus, using audiology, distortion product otoacoustic emissions and transient evoked otoacoustic emissions.

Study design:

Prospective, case–control study.

Methods:

The study included 26 randomised patients with systemic lupus erythematosus (52 ears) and 30 healthy control subjects (60 ears). Pure tone audiometry was performed at 250 and 500 Hz and at 1, 2, 4, 6, 8, 10, 12, 14 and 16 kHz. Distortion product otoacoustic emissions and transient evoked otoacoustic emissions were measured using Biologic System equipment with Scout Acoustic Emissions System software.

Results:

The distortion product otoacoustic emission signal responses were significantly different only at 750 Hz, while the distortion product otoacoustic emission signal–noise ratios were significantly different at 750 Hz and 6 kHz (p < 0.05), comparing patients and controls. The transient evoked otoacoustic emission signal–noise ratios were significantly different at 2 and 3 kHz, comparing patients and controls (p < 0.05). The transient evoked otoacoustic emission total signal–noise ratios were significantly different, comparing patients and controls (p < 0.05). In addition, the pure tone audiometry thresholds were significantly different at 250 and 500 Hz and at 1, 2, 10 and 12 kHz, comparing patients and controls (p < 0.05).

Conclusion:

Our findings do not completely agree with those of previous temporal bone histopathological studies. However, our results do support a general picture of low frequency hearing loss in systemic lupus erythematosus patients. We consider these results to be related to endolymphatic and cochlear hydrops, and we suggest that electrocochleography could be performed in further studies for clarification of this subject.

Keywords

Systemic Lupus ErythematosusHearing LossInner EarOtoacoustic Emissions
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 124 , Issue 2 , February 2010 , pp. 137 - 140
Copyright
Copyright © JLO (1984) Limited 2009

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