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Racial disparities in papillary thyroid microcarcinoma survival

Published online by Cambridge University Press:  05 December 2016

U C Megwalu  and
A T Saini
U C Megwalu*
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Stanford University School of Medicine, California, USA
A T Saini
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, USA
*
Address for correspondence: Dr Uchechukwu C Megwalu, Department of Otolaryngology – Head and Neck Surgery, Stanford University School of Medicine, 801 Welch Road, Stanford, CA 94305, USA Fax: +1 650 725 8502 E-mail: [email protected]
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Abstract

Objective:

To evaluate the impact of race on survival in patients with papillary thyroid microcarcinoma.

Methods:

The study cohort included 17 668 patients diagnosed with papillary thyroid microcarcinoma between 1988 and 2009, identified in the Surveillance, Epidemiology, and End Results 18 database of the National Cancer Institute.

Results:

Black patients had lower overall survival than other racial groups (p < 0.001). Black patients had significantly worse overall survival (hazard ratio = 2.59) after adjusting for sex, marital status, age, year of diagnosis, multifocal disease and type of surgery. A subset analysis of Black patients revealed no significant difference in overall survival for total thyroidectomy versus lobectomy (p = 0.15).

Conclusion:

Black race is a negative prognostic factor in thyroid cancer, which cannot be explained by advanced disease stage. Further research on mechanisms by which race affects survival is needed to reveal areas of opportunity for interventions aimed at reducing health disparities in cancer care.

Keywords

Thyroid NeoplasmsHealth Status DisparitiesMinority HealthSEER Program
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 131 , Issue 1 , January 2017 , pp. 83 - 87
Copyright
Copyright © JLO (1984) Limited 2016 

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