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Primary extramedullary plasmacytoma in the middle ear: differential diagnosis and management

Published online by Cambridge University Press:  29 June 2007

D. C. Kandiloros ,
T. P. Nikolopoulos ,
E. A. Ferekidis ,
A. N. Kaloterakis ,
C. P. Papadimitriou  and
G. K. Adamopoulos
D. C. Kandiloros
Affiliation:
Department of Otolaryngology, Athens University School of Medicine, Athens, Greece
T. P. Nikolopoulos*
Affiliation:
Department of Otolaryngology, Athens University School of Medicine, Athens, Greece
E. A. Ferekidis
Affiliation:
Department of Otolaryngology, Athens University School of Medicine, Athens, Greece
A. N. Kaloterakis
Affiliation:
Department of Internal Medicine, Athens University School of Medicine, Athens, Greece.
C. P. Papadimitriou
Affiliation:
Pathology Department, Ippokration General Hospital, Athens, Greece.
G. K. Adamopoulos
Affiliation:
Department of Otolaryngology, Athens University School of Medicine, Athens, Greece
*
Thomas P. Nikolopoulos, M.D., Ph.D., 120 Michael Boda Street, Athens 104-46, Greece.
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Abstract

Abstract: Primary extramedullary plasmacytoma (PEP) is an uncommon neoplasm of plasma cell origin which afflicts the head and neck mainly. In this study we report a rare case of a 34-year-old man who presented with left ear tinnitus, hearing loss, blocked feeling and headache. Exploratory tympanotomy revealed a mass extending into the attic and the mastoid antrum. Following canal wall-up mastoidectomy, the tumour was carefully removed. Histological examination (including immunoperoxidase staining) and thorough clinical, laboratory and radiological evaluation revealed an exclusively cytoplasmic monoclonal IgG immunoglobulin PEP. The combination of surgery (including a second-look procedure) and radiotherapy used in this case may be an over-treatment. However, the patient is still disease-free seven years after his first admission to hospital.

Keywords

PlasmacytomaEar neoplasms
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 108 , Issue 10 , October 1994 , pp. 868 - 870
Copyright
Copyright © JLO (1984) Limited 1994

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