Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-25T19:48:15.213Z Has data issue: false hasContentIssue false

A preliminary report on the combination of initial chemotherapy and radiotherapy for advanced head and neck cancer

Published online by Cambridge University Press:  29 June 2007

R. Sergeant
Affiliation:
Brighton
G. Deutsch
Affiliation:
Brighton

Abstract

A Retrospective review of 45 patients with advanced squamous cell carcinoma of the head and neck treated by a combination of initial chemotherapy (Price and Hill Schedule A) followed by radiotherapy is presented. The regime produced excellent immediate palliation with a tumour control of 50 per cent, and a disease-free survival of 33 per cent at one year and 27 per cent at two years. Treatment morbidity was minimal in an aged patient group.

Type
Research Article
Copyright
Copyright © JLO (1984) Limited 1981

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Catterall, M., Bewley, D. and Sutherland, I. (1977) Second report on results of a randomized clinical trial of fast neutrons compared with X- or gamma-rays in the treatment of advanced tumours of the head and neck. British Medical Journal, 1, 1642.CrossRefGoogle ScholarPubMed
O'Connor, A. D., Clifford, P., Durden-Smith, J., Edwards, E., Hollis, B. A. and Dalley, V. M. (1977) Synchronous VBM and radiotherapy in the treatment of squamous cell carcinoma of the head and neck. Clinical Otolaryngology, 1, 347.CrossRefGoogle Scholar
Price, L. A., Hill, B. T., Calvert, A. H., Shaw, H. J. and Hughes, K. B. (1975) Kinetically-based multiple drug treatment for advanced head and neck cancer. British Medical Journal, 3, 1011.CrossRefGoogle ScholarPubMed