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Predictors of disease progression after endoscopic sinus surgery in patients with chronic rhinosinusitis

Published online by Cambridge University Press:  20 June 2019

K Tsuzuki*
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Hyogo College of Medicine, Nishinomiya, Japan
K Hashimoto
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Hyogo College of Medicine, Nishinomiya, Japan
K Okazaki
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Hyogo College of Medicine, Nishinomiya, Japan
H Nishikawa
Affiliation:
Center for Clinical Research and Education, Hyogo College of Medicine, Nishinomiya, Japan
M Sakagami
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Hyogo College of Medicine, Nishinomiya, Japan
*
Author for correspondence: Dr Kenzo Tsuzuki, Department of Otorhinolaryngology – Head and Neck Surgery, Hyogo College of Medicine, 1-1 Mukogawa, Nishinomiya, Hyogo 663-8501, Japan E-mail: [email protected] Fax: +81 798 41 8976

Abstract

Objective

This study aimed to determine the predictors of disease progression after functional endoscopic sinus surgery in patients with chronic rhinosinusitis.

Method

A total of 281 adult chronic rhinosinusitis patients who underwent primary bilateral functional endoscopic sinus surgery between 2007 and 2017 and had at least 12 months of follow-up endoscopic evaluation were examined. Patients were divided into eosinophilic (n = 205) and non-eosinophilic chronic rhinosinusitis groups (n = 76). In order to determine adverse factors, post-operative endoscopic appearance scores were analysed in relation to the pre- and intra-operative findings using multiple regression analyses.

Results

The post-operative course of eosinophilic cases deteriorated over time, like the early period for non-eosinophilic cases. Frontal sinus polyps recurred early in eosinophilic chronic rhinosinusitis. Multivariate analyses indicated young adulthood, asthma, high computed tomography score and frontal sinus polyps as significant adverse predictors.

Conclusion

Early, appropriate estimation of sinonasal conditions appears to be crucial for successful surgical management of chronic rhinosinusitis.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited, 2019 

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Footnotes

Dr K Tsuzuki takes responsibility for the integrity of the content of the paper

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