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Post coronavirus disease mucormycosis: a deadly addition to the pandemic spectrum

Part of: JLO Coronavirus Collection

Published online by Cambridge University Press:  08 April 2021

S Sharma ,
M Grover ,
S Bhargava ,
S Samdani  and
T Kataria
S Sharma
Affiliation:
Department of Otorhinolaryngology and Head Neck Surgery, Sawai Man Singh Medical College and Hospital, Jaipur, India
M Grover*
Affiliation:
Department of Otorhinolaryngology and Head Neck Surgery, Sawai Man Singh Medical College and Hospital, Jaipur, India
S Bhargava
Affiliation:
Department of Pathology, Sawai Man Singh Medical College and Hospital, Jaipur, India
S Samdani
Affiliation:
Department of Otorhinolaryngology and Head Neck Surgery, Sawai Man Singh Medical College and Hospital, Jaipur, India
T Kataria
Affiliation:
Department of Otorhinolaryngology and Head Neck Surgery, Sawai Man Singh Medical College and Hospital, Jaipur, India
*
Author for correspondence: Dr Mohnish Grover, 8/250, Captain Amit Bharadwaj Marg, Malviya Nagar, Jaipur, Rajasthan, India E-mail: [email protected]
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Abstract

Objective

To study the possible association between invasive fungal sinusitis (mucormycosis) and coronavirus disease.

Methods

A prospective observational study was conducted at a tertiary care centre over four months, involving all patients with mucormycosis of the paranasal sinuses suffering from or having a history of coronavirus disease infection.

Results

Twenty-three patients presented with mucormycosis, all had an association with coronavirus disease 2019. The ethmoids (100 per cent) were the most common sinuses affected. Intra-orbital extension was seen in 43.47 per cent of cases, while intracranial extension was only seen in 8.69 per cent. Diabetes mellitus was present in 21 of 23 cases, and was uncontrolled in 12 cases. All patients had a history of steroid use during their coronavirus treatment.

Conclusion

New manifestations of coronavirus disease 2019 are appearing over time. The association between coronavirus and mucormycosis of the paranasal sinuses must be given serious consideration. Uncontrolled diabetes and over-zealous use of steroids are two main factors aggravating the illness, and both of these must be properly checked.

Keywords

CoronavirusCovid-19SARS-CoV-2 InfectionMucormycosisMucorales Infection
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 135 , Issue 5 , May 2021 , pp. 442 - 447
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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Footnotes

Dr S Sharma takes responsibility for the integrity of the content of the paper

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