Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-23T18:42:14.248Z Has data issue: false hasContentIssue false
  • English
  • Français

Parotid lymphoepithelial cysts in human immunodeficiency virus: a review

Published online by Cambridge University Press:  29 October 2013

D Sujatha ,
K Babitha ,
R S Prasad  and
A Pai
D Sujatha
Affiliation:
Department of Oral Medicine and Radiology, The Oxford Dental College, Bommanahalli, Bangalore, Karnataka, India
K Babitha*
Affiliation:
Department of Oral Medicine and Radiology, The Oxford Dental College, Bommanahalli, Bangalore, Karnataka, India
R S Prasad
Affiliation:
Department of Oral Medicine and Radiology, The Oxford Dental College, Bommanahalli, Bangalore, Karnataka, India
A Pai
Affiliation:
Department of Oral Medicine and Radiology, The Oxford Dental College, Bommanahalli, Bangalore, Karnataka, India
*
Address for correspondence: Dr K Babitha, Department of Oral Medicine and Radiology, The Oxford Dental College, Bommanahalli, Hosur Road, Bangalore 560068, Karnataka, India E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Background:

Many patients with human immunodeficiency virus present with atypical features. Early indicators of human immunodeficiency virus are scarce and hence most affected patients are diagnosed in the later stages of the disease, which is associated with poor prognosis. Salivary gland disease usually develops before acquired immunodeficiency syndrome, and is sometimes the first manifestation of human immunodeficiency virus infection. Salivary gland lesions include benign lymphoepithelial cysts of the parotid gland, which are seen in 3–6 per cent of patients. Many of the reported lesions are diagnosed on routine examination.

Objective:

This review aimed to highlight the association between parotid gland benign lymphoepithelial cyst and human immunodeficiency virus infection, in order to aid early diagnosis and management of the disease.

Conclusion:

Human immunodeficiency virus testing is recommended for patients with benign lymphoepithelial cysts, as this can often be the first indication of human immunodeficiency virus infection. Benign lymphoepithelial cysts are important diagnostic and prognostic indicators in human immunodeficiency virus infection.

Keywords

Parotid GlandCystHIVDiagnosis
Type
Review Articles
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 11 , November 2013 , pp. 1046 - 1049
Copyright
Copyright © JLO (1984) Limited 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Maremonti, P, Colmenero Ruiz, C, Patron, MM, Zupi, A, Longo, F, Califano, L. HIV-related benign lymphoepithelial cysts of the parotid gland. Minerva Stomatol 2000;49:383–8Google Scholar
2Kothari, KS, Madiwale, CV, Deshpande, AA. Cystic lymphoepithelial lesion of the parotid as an early indicator of HIV infection. J Postgrad Med 2009;55:135–6CrossRefGoogle ScholarPubMed
3Kabenge, C, Ng, S, Muyinda, Z, Ameda, F. Diagnostic ultrasound patterns of parotid glands in human immunodeficiency virus-positive patients in Mulago, Uganda. Dentomaxillofac Radiol 2010;39:389–99CrossRefGoogle ScholarPubMed
4Kumar, VV, Sharma, N. Parotid lymphoepithelial cysts as an indicator of HIV infection. J Can Dent Assoc 2011;77:b28Google ScholarPubMed
5Steehler, MK, Steehler, MW, Davison, SP. Benign lymphoepithelial cysts of the parotid: long-term surgical results. HIV AIDS (Auckl) 2012;4:81–6Google ScholarPubMed
6Tiwari, A, Kini, H, Pai, RR, Rau, AR. HIV lymphadenitis of the salivary gland: a case with cytological and histological correlation. J Cytol 2009;26:146–8CrossRefGoogle ScholarPubMed
7Krishnamurthy, JM, Gowdanakatte, MC, Gubanna, MV. Lymphoepithelial cyst - a sign of unappreciated HIV infection. Indian J Sex Transm Dis 2011;32:60–2CrossRefGoogle ScholarPubMed
8Kessler, AT, Kourtis, AP, Jurado, R. Man with progressive swelling of the face and neck. Clin Infect Dis 2003;37:1565–7CrossRefGoogle ScholarPubMed
9Miller, MA. Pondering parotid masses. Can J Infect Dis 2001;12:107–15Google ScholarPubMed
10Thomas, BP, Wushensky, CA. HIV-related benign lymphoepithelial lesions. Appl Radiol 2012;41:29–30CrossRefGoogle Scholar
11Meyer, E, Lubbe, DE, Fagan, JJ. Alcohol sclerotherapy of human immunodeficiency virus related parotid lymphoepithelial cysts. J Laryngol Otol 2009;123:422–5CrossRefGoogle ScholarPubMed
12Ellis, GL. Lymphoid lesions of salivary glands: malignant and benign. Med Oral Patol Oral Cir Bucal 2007;12:E479–85Google ScholarPubMed
13Alves, CAF, Ribeiro Júnior, O, Borba, AM, Souza, SCOM, Naclério-Homem, MG. Parotid lymphoepithelial cyst in non-HIV patient. J Clin Exp Dent 2011;3(suppl 1):e400–3CrossRefGoogle Scholar
14Naidoo, M, Singh, B, Ramdial, PK, Moodley, J, Allopi, L, Lester, B. Lymphoepithelial lesions of the parotid gland in the HIV era – a South African experience. S Afr J Surg 2007;45:136–40Google Scholar
15Tripathi, AK, Gupta, N, Ahmad, R, Bhandari, HS, Kalra, P. HIV disease presenting as parotid lymphoepithelial cysts: a presumptive diagnosis of diffuse infiltrative lymphocytic syndrome (DILS). J Assoc Physicians India 2004;52:921–3Google ScholarPubMed
16Chhieng, DC, Cangiarella, FJ, Cohen, JM. Fine-needle aspiration cytology of lympho-proliferative lesions involving the major salivary glands. Am J Clin Pathol 2000;113:563–71CrossRefGoogle Scholar
17Martinoli, C, Pretolesi, F, Del Bono, V, Derchi, LE, Mecca, D, Chiaramondia, M. Benign lymphoepithelial parotid lesions in HIV-positive patients: spectrum of findings at gray-scale and Doppler sonography. AJR Am J Roentgenol 1995;165:975–9CrossRefGoogle ScholarPubMed
18Maiorano, E, Favia, G. Lymphoepithelial cysts of salivary glands in HIV-infected patients: clinico-pathological and immunohistochemical features. Boll Soc Ital Biol Sper 1994;70:287–94Google ScholarPubMed
19Mandel, L, Tomkoria, A. Differentiating HIV-1 parotid cysts from papillary cystadenoma lymphomatosum. J Am Dent Assoc 2000;131:772–6CrossRefGoogle ScholarPubMed