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Parathyroid carcinoma: a report of two cases and a concise review and update of the literature

Published online by Cambridge University Press:  08 March 2006

Humera Babar-Craig
Affiliation:
Department of Otorhinolaryngology, Royal Free Hospital, London, UK
Alberto Quaglia
Affiliation:
Department of Histopathology, Royal Free Hospital, London, UK
Michael Stearns
Affiliation:
Department of Otorhinolaryngology, Royal Free Hospital, London, UK

Abstract

Parathyroid carcinoma is very rare and when diagnosed can be difficult to treat as more than 50 per cent have persistent or recurrent disease. Patients generally present with profound symptoms of hypercalcaemia and a palpable neck mass. We describe a case of parathyroid carcinoma in primary hyperparathyroidism and a case in tertiary hyperparathyroidism in a renal dialysis patient. Most studies in the literature are retrospective but recent trends in presentation, treatment options and complications have been reviewed and are summarized in this paper.

Type
Research Article
Copyright
© 2005 Royal Society of Medicine Press

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