Hostname: page-component-cd9895bd7-gbm5v Total loading time: 0 Render date: 2024-12-29T05:00:57.506Z Has data issue: false hasContentIssue false
  • English
  • Français

Papillary and follicular thyroid carcinoma: the treatment results of 357 patients at the National Kyushu Cancer Centre of Japan

Published online by Cambridge University Press:  29 June 2007

Kimimasa Yasumoto ,
Chisato Miyagi ,
Tadashi Nakashima ,
Hideo Baba  and
Yasaburoh Katsuta
Kimimasa Yasumoto
Affiliation:
Department of Head and Neck Surgery, National Kyushu Cancer Centre, Notame 3-1-1, Minami-ku, Fukuoka 815Japan
Chisato Miyagi
Affiliation:
Department of Head and Neck Surgery, National Kyushu Cancer Centre, Notame 3-1-1, Minami-ku, Fukuoka 815Japan
Tadashi Nakashima*
Affiliation:
Department of Head and Neck Surgery, National Kyushu Cancer Centre, Notame 3-1-1, Minami-ku, Fukuoka 815Japan
Hideo Baba
Affiliation:
Department of Gastroenterological Surgery, National Kyushu Cancer Centre, Notame 3-1-1, Minami-ku, Fukuoka 815Japan
Yasaburoh Katsuta
Affiliation:
Departmentt of Pathology, National Kyushu Cancer Centre, Notame 3-1-1, Minami-ku, Fukuoka 815, Japan
*
Address for correspondence: Tadashi Nakashima, M.D., Department of Head and Neck Surgery, National Kyushu Cancer Centre, Notame 3-1-1, Minami-ku, Fukuoka 815, Japan. Fax: (092) 551-4585.
Get access Rights & Permissions [Opens in a new window]

Abstract

During the period from April 1974 to March 1993, 357 patients received surgical treatment for papillary and follicular carcinoma of the thyroid gland at the Department of Head and Neck Surgery of National Kyushu Cancer Centre, Japan. In this paper, we review the various clinico-pathological features of these patients and analyse their influence on patient survival. While the majority of the patients' ages ranged from the third through seventh decade, only the patients older than 40 years old died. In papillary carcinomas, there was a statistically significant difference in the survival rate between younger (less than 45 years old) and older (45 years of age or older) patients. The rate of patients who died of thyroid cancer also increased in the cases with extra-thyroidal tumour invasion, and metastasis to distant organs. A multivariate analysis also showed that the age, extrathyroidal invasion and distant metastasis are significant prognostic factors. However, sex, histology and lymph node metastasis were not prognostic factors for survival.

Keywords

Thyroid neoplasmsCarcinoma, papillaryCarcinoma, follicularPrognosis
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 110 , Issue 7 , July 1996 , pp. 657 - 662
Copyright
Copyright © JLO (1984) Limited 1996

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Akslen, L. A. (1993) Prognostic importance of histologic grading in papillary thyroid carcinoma. Cancer 72: 2680–2685.3.0.CO;2-D>CrossRefGoogle ScholarPubMed
Bacourt, F., Asselain, B., Savoie, J. C., D'Hubert, E., Massom, J. P., Doucet, G., Leger, A., Gamier, H. (1986) Multifactorial study of prognostic factors in differentiated thyroid carcinoma and re-evaluation of the importance of age. British Journal of Surgery 73: 274–277.CrossRefGoogle ScholarPubMed
Beenken, S., Guillamondegui, O., Shallenberger, R., Knapp, C, Ratter, D., Goepfert, H. (1989) Prognostic factors in patients dying of well-differentiated thyroid cancer. Archives of Otolaryngology, Head and Neck Surgery 115: 326–330.CrossRefGoogle ScholarPubMed
Bohr, D. P., Green, S. B., Dor, P., Williams, E. D., Colon, J., van Jailhouse, H. A., Mayer, M., Sylvester, R. J., van Glabekke, M. (1979) A prognostic index for thyroid carcinoma: A study of the EORTC Thyroid Cancer Cooperative Group. European Journal of Cancer 15: 1033–1041.Google Scholar
Cady, B., Wool, M. S., Salzman, F. A., Weber, J. (1979) Risk factor analysis in differentiated thyroid cancer. Cancer 43: 810–820.3.0.CO;2-B>CrossRefGoogle ScholarPubMed
Carcangiu, M. L., Zampi, G., Pupi, A., Castagnoli, A., Rosai, J. (1985) Papillary carcinoma of the thyroid: A clinicopathologic study of 241 cases treated at the University of Florence, Italy. Cancer 55: 805–828.3.0.CO;2-Z>CrossRefGoogle ScholarPubMed
Cox, D. R. (1972) Regression models and life table. Journal of Royal Statistical Society Series B 34: 187–220.Google Scholar
Crile, G., Pontius, K. I., Hawk, W. A. (1985) Factors influencing the survival of patients with follicular carcinoma of the thyroid gland. Surgery, Gynecology and Obstetrics 160: 409–413.Google ScholarPubMed
Harley, E. H., Daly, E. G., Hodge, J. W. (1988) Thyroglobulin assays in the post-operative management of differentiated thyroid cancer. Archives of Otolarynology, Head and Neck Surgery 114: 333–335.CrossRefGoogle Scholar
Hermanek, P., Sobin, L. H. (1987) TNM Classification of Malignant tumours. In International Union Against Cancer. 4th Edition. (Hermanek, P., Sobin, L. H., eds.), Springer Verlag, Berlin, pp 33–35.Google Scholar
Mazzaferri, E. L., Young, R. L. (1981) Papillary thyroid carcinoma: A 10 year follow-up report of the impact of therapy in 576 patients. American Journal of Medicine 70: 511–518.CrossRefGoogle ScholarPubMed
McCaffrey, T. V., Bergstrain, E. J., Hay, I. D. (1994) Locally invasive papillary thyroid carcinoma: 1940–1990. Head and Neck 16: 165–172.CrossRefGoogle ScholarPubMed
Samaan, N. A., Maheshwari, Y. K., Nador, S., Hill, C. S., Schultz, J. P. N., Haynie, T. P., Hickey, R. C., Clark, R. L., Goepfert, H., Ibanez, M. L., Litton, C. E. (1983) Impact of therapy for differentiated carcinoma of the thyroid. An analysis of 706 cases. Journal of Clinical Endocrinology and Metabolism 56: 1131–1138.CrossRefGoogle ScholarPubMed
Schroder, S., Bocker, W., Dralle, H., Kortmann, K., Stern, C. (1985) The encapsulated papillary carcinoma of the thyroid. Cancer 54: 90–93.3.0.CO;2-0>CrossRefGoogle Scholar
Segal, K., Arad, A., Lubin, E., Shpitzer, T., Hadar, T., Feinmesser, R. (1994) Follicular carcinoma of the thyroid. Head and Neck 16: 533–538.CrossRefGoogle ScholarPubMed
Simpson, W. J., McKinney, S. E., Carruthers, J. S., Gospodarowicz, M. K., Sutchiffe, S. B., Panzarella, T. (1987) Papillary and follicular thyroid cancer – prognostic factors in 1578 patients. American Journal of Medicine 83: 479–488.CrossRefGoogle Scholar
Tubiana, M., Schlumberger, M., Rougier, P., Laplanche, A., Benhamon, E., Gardet, P., Caillon, B., Travagli, J. P., Parmentier, C. (1985) Long-term results and prognostic factors in patients with differentiated thyroid carcinoma. Cancer 55: 794–804.3.0.CO;2-Z>CrossRefGoogle ScholarPubMed
Ward, P. H. (1986) The surgical treatment of thyroid cancer. Archives of Otolaryngology, Head and Neck Surgery 112: 1204–1206.CrossRefGoogle ScholarPubMed