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Ototoxicity of ethacrynic acid

Published online by Cambridge University Press:  29 June 2007

L. P. Rybak
L. P. Rybak*
Affiliation:
Springfield, Illinois, U.S.A.
*
Leonard P. Rybak, M.D., PH.D., Associate Professor, Division of Otolaryngology, Southern Illinois University School of Medicine, P.O.Box 3926, Springfield, Illinois 62708, U.S.A.
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Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 102 , Issue 6 , June 1988 , pp. 518 - 520
Copyright
Copyright © JLO (1984) Limited 1988

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References

Ahokas, J. T., Davies, C., Ravencroft, P. J. and Emerson, B. T. (1984) Inhibition of soluble glutathione S-transferase by diuretic drugs. Biochemical Pharmacology, 33: 1929–1932.CrossRefGoogle ScholarPubMed
Arnold, W., Nadol, J. B. Jr. and Weidauer, H. (1981) Ultrastructural histopathology in a case of human ototoxicity due to loop diuretics. Acta Otolaryngologica, 91: 399–414.CrossRefGoogle Scholar
Asakuma, S. and Snow, J. B. Jr. (1980) Effects of furosemide and ethacrynic acid on the endocochlear direct current potential in normal and kanamycin sulfate-treated guinea pigs. Otolaryngology Head and Neck Surgery, 88: 188–193.CrossRefGoogle ScholarPubMed
Bagger-Sjoback, D., Filipek, C. S. and Schacht, J. (1980) Characteristics and drug responses of cochlear and vestibular adenylate cyclase. Archives of Otorhinolaryngology, 228: 217–222.CrossRefGoogle ScholarPubMed
Bosher, S. K. (1980a) The nature of the ototoxic actions of ethacrynic acid upon the mammalian endolymph system. II. Structural-functional correlates in the stria vascularis. Acta Otolaryngologica (Stockholm), 90: 40–59.CrossRefGoogle ScholarPubMed
Bosher, S. K. (1980b) The nature of the ototoxic actions of ethacrynic acid upon the mammalian endolymph system. I. Functional Aspects. Acta Otolaryngologica (Stockholm), 89: 407–418.CrossRefGoogle ScholarPubMed
Bosher, S. K., Smith, C. and Warren, R. L. (1973) The effects of ethacrynic acid upon the cochlear and the stria vascularis. A preliminary report. Acta Otolaryngologica (Stockholm), 75: 184–191.CrossRefGoogle ScholarPubMed
Boston Collaborative Drug Surveillance Program (1973) Druginduced deafness: A co-operative study. Journal of the American Medical Association, 224: 515–516CrossRefGoogle Scholar
Brown, R. D. and McElwee, T. T. Jr. (1972) Effects of intraarterially and intravenously administered ethacrynic acid and furosemide on cochlear N1 in cats. Toxicology and Applied Pharmacology, 22: 589–594.Google ScholarPubMed
Brummett, R., Smith, C. A., Ueno, Y., Cameron, S. and Richter, R. (1977) The delayed effects of ethacrynic acid on the stria vascularis of the guinea pig. Acta Otolaryngologica (Stockholm), 83: 98–112.CrossRefGoogle ScholarPubMed
Burg, M. and Green, N. (1973) Effects of ethacrynic acid on the thick ascending limb of Henle's loop. Kidney International, 4: 301–308.CrossRefGoogle ScholarPubMed
Federspil, P. and Mausen, H. (1973) Experimented Untersuchungen uber die Ototoxicität eines starken salidiureticums (Ethacrynsaure). Monatschrift fur Ohrenheilkunde Wien, 107: 256–263.Google Scholar
Goldman, W. J., Bielinski, T. C. and Mattis, P. A. (1973) Cochlear microphonic potential respose of the dog to diuretic compounds. Toxicology and Applied Pharmacology, 25: 259–266.CrossRefGoogle Scholar
Hanzelik, E. and Peppercorn, M. (1969) Deafness after ethacrynic acid. Lancet, 1: 416.CrossRefGoogle ScholarPubMed
Hoffman, D. W., Whitworth, C. A., Joyner-Triplett, N. and Rybak, L. P. (1986) Gluthathione depletion markedly enhances drug-induced hearing loss–possible mechanism of ototoxicity. Abstracts of the Society for Neuroscience Meeting, 12: 1561Google Scholar
Johnson, A. H. and Hamilton, C. H. (1970) Kanamycin ototoxicity: possible potentiation by othe drugs. Southern Medical Journal, 63: 511–513.CrossRefGoogle Scholar
Koechel, D. A. (1981) Ethacrynic acid and related diuretics: Relationship of structure to beneficial and detrimental actions. Annual Review of Pharmacology, 21: 265–295.CrossRefGoogle ScholarPubMed
Komune, S. and Snow, J. B. Jr. (1981) Potentiating effects of cisplatin and ethacrynic acid in ototoxicity. Archives of Otolaryngology, 107: 594–597.CrossRefGoogle ScholarPubMed
Komune, S. and Morimitsu, T. (1985) Dissociation of the cochlear microphonics and endocochlear potential after ethacrynic acid injection. Archives of Otorhinolaryngology, 241: 149–156.CrossRefGoogle Scholar
Kusakari, J., Ise, I., Comegys, T. V., Thalmann, I. and Thalmann, R. (1978) Effect of ethacrynic acid, furosemide and obatain upon the endolymphatic potential and upon high energy phosphates of the stria vascularis. Laryngoscope, 88: 12–37.CrossRefGoogle ScholarPubMed
Lant, A. (1986) Diuretic drugs. Progress in clinical pharmacology. Drugs 31, (Supplement 4): 40–55.Google ScholarPubMed
Maher, J. F. and Schreiner, G. E. (1965) Studies on ethacrynic acid in patients with refractory edema. Annals of Internal Medicine, 62: 15–29.CrossRefGoogle ScholarPubMed
Marcus, D. (1986) In Neurobiology of Hearing: The cochlea (Altschuler, R. A., Hoffman, D. W., and Bobbin, R. P. editors) pp. 123–137, Raven Press, New York.Google Scholar
Marks, S. C. and Schacht, J. (1981) Effects of ototoxic diuretics in cochlear NA+–K+– ATPase and adenylate cyclase. Scandinavian Audiology, Supplement 14: 131–137.Google ScholarPubMed
Mathog, R. H. and Klein, W. J. (1969) Ototoxicity of ethacrynic acid and aminolgoycoside antibiotics in uremia. New England Journal of Medicine, 280: 1223–1224.CrossRefGoogle ScholarPubMed
Mathog, R. H., Thomas, W. G. and Hudson, W. R., (1970) Ototoxicity of new and potent diuretics. Archives of Otolaryngology, 92: 7–13.CrossRefGoogle ScholarPubMed
Matz, G. J., Beal, D. D. and Krames, L. (1969) Ototoxicity of ethacrynic acid demonstrated in a human temporal bone. Archives of Otolaryngology, 90: 152–159.CrossRefGoogle Scholar
Matz, G. J. (1976) The ototoxic effects of ethacrynic acid in man and animals. Laryngoscope, 86: 1065–1086.Google Scholar
Melichar, I. and Syka, J. (1978) The effects of ethacrynic acid upon the potassium concentration in guinea pig inner ear fluids. Hearing Research, 1: 35–41.CrossRefGoogle Scholar
Meriwether, W. D., Mangi, R. J. and Serpick, A. A. (1971) Deafness following standard intraveneous dose of ethacrynic acid. Journal of American Medical Association, 216: 795–798.CrossRefGoogle ScholarPubMed
Ng, P. S. Y., Conley, C. E. and Ing, T. S. (1969) Deafness after ethacrynic acid. Lancet, 1: 673–674.CrossRefGoogle ScholarPubMed
Pillay, V. K., Schwartz, F. D., Aimi, K. and Kark, R. M. (1969) Transient and permanent deafness following treatment with ethacrynic acid in renal failure. Lancet, 1: 77–79.CrossRefGoogle ScholarPubMed
Quick, C. A. and Duvall, A. J. (1970) Early changes in the cochlear duct from ethacrynic acid: An electron-microscopic evaluation. Laryngoscope, 80: 954–965.CrossRefGoogle Scholar
Rybak, L. P. (1986a) Drug Ototoxicity. Annual Review of Pharmacology and Toxicology, 26: 79–99.CrossRefGoogle ScholarPubMed
Rybak, L. P. (1986b) In Neurobiology of Hearing: The Cochlea (Altschuler, R. A., Hoffman, D. W. and Bobbin, R. P., editors) pp. 441–454, Raven Press, New York.Google Scholar
Schlatter, E., Greger, R. and Weidtke, C. (1983) Effects of ‘high ceiling’ diuretics on active salt transport in the cortical thick ascending limb of Henle's loop of the rabbit kidney. Correlation of chemical structure and inhibitory potency. Pfluegers Archives, 396: 210–217.CrossRefGoogle ScholarPubMed
Schmidt, P. and Friedman, I. S. (1967) Adverse effects of ethacrynic acid. New York State Journal of Medicine, 67: 1438–1442.Google ScholarPubMed
Schneider, W. J. and Becker, E. L. (1966) Acute transient hearing loss after ethacrynic acid therapy. Archives of Internal Medicine, 117: 715–717.CrossRefGoogle ScholarPubMed
Schnieders, J. R. and Ludens, J. H. (1980) Comparison of effects of standard diuretics and indacrinone in isolated toad cornea and bladder. American Journal of Physiology, 238: R70–R75.Google Scholar
Sellick, P. M. and Bock, G. R. (1974) Evidence for an electrogenic potassium pump as the origin of the positive component for the endocochlear potential. Pfluegens Archives, 352: 351–361.CrossRefGoogle ScholarPubMed
Silverstein, H. and Yules, R. (1971) The effects of diuretics on cochlear potentials and inner ear fluids. Laryngoscope, 81: 873–888.CrossRefGoogle ScholarPubMed
Slone, D., Jick, H. and Lewis, G. P. (1969) Intravenously given ethacrynic acid and gastrointestinal bleeding. Journal of the American Medical Association, 209: 1668–1671.CrossRefGoogle ScholarPubMed
Syka, J. and Melichar, I. (1981) Comparison of the effects of furosemide and ethacrynic acid upon the cochlear function in the guinea pig. Scandinavian Audiology, Supplement 14: 63–69.Google ScholarPubMed
West, B. A., Brummett, R. E. and Himes, D. L. (1973) Interaction of kanamycin and ethacrynic acid. Archives of Otolaryngology, 98: 32–38.CrossRefGoogle ScholarPubMed
Yamada, T. and Kaplowitz, N. (1980) Binding of ethacrynic acid to hepatic glutathione S-tranferases in vivo in the rat. Biochemical Pharmacology, 29: 1205–1208.CrossRefGoogle Scholar